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Compile Data Set for Download or QSAR

Found 327 hits Enz. Inhib. hit(s) with all data for entry = 9180   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM447681
PNG
(US10689367, Example 1.0)
Show SMILES CO[C@@H]1CCC[C@H](OC)[C@H]1n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(C)cn2)nnc1-c1cncc(C)c1 |r|
Show InChI InChI=1S/C25H35N7O4S/c1-15-10-19(14-26-11-15)24-29-30-25(32(24)22-20(35-5)8-7-9-21(22)36-6)31-37(33,34)18(4)17(3)23-27-12-16(2)13-28-23/h10-14,17-18,20-22H,7-9H2,1-6H3,(H,30,31)/t17-,18-,20-,21+,22+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447682
PNG
(US10689367, Example 2.0)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)n1CC1COC1 |r|
Show InChI InChI=1S/C20H24ClN7O4S/c1-12(18-22-7-15(21)8-23-18)13(2)33(29,30)27-20-26-25-19(28(20)9-14-10-32-11-14)16-5-4-6-17(24-16)31-3/h4-8,12-14H,9-11H2,1-3H3,(H,26,27)/t12-,13-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447683
PNG
(US10689367, Example 3.0)
Show SMILES COCCn1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C19H24ClN7O5S/c1-12(16(32-4)17-21-10-13(20)11-22-17)33(28,29)26-19-25-24-18(27(19)8-9-30-2)14-6-5-7-15(23-14)31-3/h5-7,10-12,16H,8-9H2,1-4H3,(H,25,26)/t12-,16-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447684
PNG
(US10689367, Example 4.0)
Show SMILES COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C21H26ClN7O5S/c1-13(17(34-4)18-23-10-14(22)11-24-18)35(30,31)28-20-27-26-19(15-6-5-7-16(25-15)33-3)29(20)21(8-9-21)12-32-2/h5-7,10-11,13,17H,8-9,12H2,1-4H3,(H,27,28)/t13-,17-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447685
PNG
(US10689367, Example 5.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1C(CO)CO)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C19H24ClN7O6S/c1-11(16(33-3)17-21-7-12(20)8-22-17)34(30,31)26-19-25-24-18(27(19)13(9-28)10-29)14-5-4-6-15(23-14)32-2/h4-8,11,13,16,28-29H,9-10H2,1-3H3,(H,25,26)/t11-,16-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447686
PNG
(US10689367, Example 6.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C21H28ClN7O6S/c1-13(18(35-5)19-23-9-14(22)10-24-19)36(30,31)28-21-27-26-20(16-7-6-8-17(25-16)34-4)29(21)15(11-32-2)12-33-3/h6-10,13,15,18H,11-12H2,1-5H3,(H,27,28)/t13-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447687
PNG
(US10689367, Example 7.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1C1CC2(COC2)C1)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C22H26ClN7O5S/c1-13(18(34-3)19-24-9-14(23)10-25-19)36(31,32)29-21-28-27-20(16-5-4-6-17(26-16)33-2)30(21)15-7-22(8-15)11-35-12-22/h4-6,9-10,13,15,18H,7-8,11-12H2,1-3H3,(H,28,29)/t13-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447688
PNG
(US10689367, Example 8.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(C)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C21H29N7O5S/c1-14-10-23-19(24-11-14)18(33-5)15(2)34(29,30)27-21-26-25-20(17-8-6-7-9-22-17)28(21)16(12-31-3)13-32-4/h6-11,15-16,18H,12-13H2,1-5H3,(H,26,27)/t15-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447689
PNG
(US10689367, Example 9.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)nnc1-c1cncc(C)c1 |r|
Show InChI InChI=1S/C24H35N7O5S/c1-15(2)36-21(22-26-10-17(4)11-27-22)18(5)37(32,33)30-24-29-28-23(19-8-16(3)9-25-12-19)31(24)20(13-34-6)14-35-7/h8-12,15,18,20-21H,13-14H2,1-7H3,(H,29,30)/t18-,21+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447691
PNG
(US10689367, Example 10.0)
Show SMILES CCC(CC)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C21H28ClN7O4S/c1-6-15(7-2)29-20(16-9-8-10-17(25-16)32-4)26-27-21(29)28-34(30,31)13(3)18(33-5)19-23-11-14(22)12-24-19/h8-13,15,18H,6-7H2,1-5H3,(H,27,28)/t13-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447692
PNG
(US10689367, Example 11.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1C(C)C)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C19H24ClN7O4S/c1-11(2)27-18(14-7-6-8-15(23-14)30-4)24-25-19(27)26-32(28,29)12(3)16(31-5)17-21-9-13(20)10-22-17/h6-12,16H,1-5H3,(H,25,26)/t12-,16-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447693
PNG
(US10689367, Example 12.0)
Show SMILES COCCn1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(Cl)cn2)nnc1-c1cncc(C)c1 |r|
Show InChI InChI=1S/C21H28ClN7O4S/c1-13(2)33-18(19-24-11-17(22)12-25-19)15(4)34(30,31)28-21-27-26-20(29(21)6-7-32-5)16-8-14(3)9-23-10-16/h8-13,15,18H,6-7H2,1-5H3,(H,27,28)/t15-,18+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447694
PNG
(US10689367, Example 13.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(Cl)cn2)nnc1-c1cncc(C)c1 |r|
Show InChI InChI=1S/C23H32ClN7O5S/c1-14(2)36-20(21-26-10-18(24)11-27-21)16(4)37(32,33)30-23-29-28-22(17-7-15(3)8-25-9-17)31(23)19(12-34-5)13-35-6/h7-11,14,16,19-20H,12-13H2,1-6H3,(H,29,30)/t16-,20+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447695
PNG
(US10689367, Example 14.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C20H26ClN7O5S/c1-13(17(33-4)18-23-9-14(21)10-24-18)34(29,30)27-20-26-25-19(16-7-5-6-8-22-16)28(20)15(11-31-2)12-32-3/h5-10,13,15,17H,11-12H2,1-4H3,(H,26,27)/t13-,17-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447696
PNG
(US10689367, Example 15.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cncc(C)c1 |r|
Show InChI InChI=1S/C21H28ClN7O5S/c1-13-6-15(8-23-7-13)20-26-27-21(29(20)17(11-32-3)12-33-4)28-35(30,31)14(2)18(34-5)19-24-9-16(22)10-25-19/h6-10,14,17-18H,11-12H2,1-5H3,(H,27,28)/t14-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447697
PNG
(US10689367, Example 16.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccnc1 |r|
Show InChI InChI=1S/C20H26ClN7O5S/c1-13(17(33-4)18-23-9-15(21)10-24-18)34(29,30)27-20-26-25-19(14-6-5-7-22-8-14)28(20)16(11-31-2)12-32-3/h5-10,13,16-17H,11-12H2,1-4H3,(H,26,27)/t13-,17-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447698
PNG
(US10689367, Example 17.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2cnc(C)cn2)nnc1-c1cccnc1 |r|
Show InChI InChI=1S/C21H29N7O4S/c1-14-9-24-19(11-23-14)15(2)16(3)33(29,30)27-21-26-25-20(17-7-6-8-22-10-17)28(21)18(12-31-4)13-32-5/h6-11,15-16,18H,12-13H2,1-5H3,(H,26,27)/t15-,16-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447699
PNG
(US10689367, Example 18.0)
Show SMILES COCCn1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)nnc1-c1cccnc1 |r|
Show InChI InChI=1S/C18H22ClN7O3S/c1-12(16-21-10-15(19)11-22-16)13(2)30(27,28)25-18-24-23-17(26(18)7-8-29-3)14-5-4-6-20-9-14/h4-6,9-13H,7-8H2,1-3H3,(H,24,25)/t12-,13-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447700
PNG
(US10689367, Example 19.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)nnc1-c1cccnc1 |r|
Show InChI InChI=1S/C20H26ClN7O4S/c1-13(18-23-9-16(21)10-24-18)14(2)33(29,30)27-20-26-25-19(15-6-5-7-22-8-15)28(20)17(11-31-3)12-32-4/h5-10,13-14,17H,11-12H2,1-4H3,(H,26,27)/t13-,14-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447701
PNG
(US10689367, Example 20.0)
Show SMILES COCCn1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(OC)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C20H27N7O5S/c1-13(18-21-11-15(31-4)12-22-18)14(2)33(28,29)26-20-25-24-19(27(20)9-10-30-3)16-7-6-8-17(23-16)32-5/h6-8,11-14H,9-10H2,1-5H3,(H,25,26)/t13-,14-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447702
PNG
(US10689367, Example 21.0)
Show SMILES COCCn1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(OC)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C19H25N7O4S/c1-13(17-21-11-15(30-4)12-22-17)14(2)31(27,28)25-19-24-23-18(26(19)9-10-29-3)16-7-5-6-8-20-16/h5-8,11-14H,9-10H2,1-4H3,(H,24,25)/t13-,14-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447703
PNG
(US10689367, Example 22.0)
Show SMILES CCOCCn1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C20H26ClN7O4S/c1-5-32-10-9-28-19(16-7-6-8-17(24-16)31-4)25-26-20(28)27-33(29,30)14(3)13(2)18-22-11-15(21)12-23-18/h6-8,11-14H,5,9-10H2,1-4H3,(H,26,27)/t13-,14-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447704
PNG
(US10689367, Example 23.0)
Show SMILES COCCn1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(Cl)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C20H26ClN7O4S/c1-13(2)32-17(18-23-11-15(21)12-24-18)14(3)33(29,30)27-20-26-25-19(28(20)9-10-31-4)16-7-5-6-8-22-16/h5-8,11-14,17H,9-10H2,1-4H3,(H,26,27)/t14-,17+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447706
PNG
(US10689367, Example 24.0)
Show SMILES COCCn1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C21H28ClN7O5S/c1-13(2)34-18(19-23-11-15(22)12-24-19)14(3)35(30,31)28-21-27-26-20(29(21)9-10-32-4)16-7-6-8-17(25-16)33-5/h6-8,11-14,18H,9-10H2,1-5H3,(H,27,28)/t14-,18+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447707
PNG
(US10689367, Example 25.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1C(C1CC1)C1CC1)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C23H28ClN7O4S/c1-13(20(35-3)21-25-11-16(24)12-26-21)36(32,33)30-23-29-28-22(17-5-4-6-18(27-17)34-2)31(23)19(14-7-8-14)15-9-10-15/h4-6,11-15,19-20H,7-10H2,1-3H3,(H,29,30)/t13-,20-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447710
PNG
(US10689367, Example 26.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1CCSC)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C19H24ClN7O4S2/c1-12(16(31-3)17-21-10-13(20)11-22-17)33(28,29)26-19-25-24-18(27(19)8-9-32-4)14-6-5-7-15(23-14)30-2/h5-7,10-12,16H,8-9H2,1-4H3,(H,25,26)/t12-,16-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447711
PNG
(US10689367, Example 42.0)
Show SMILES COCCOc1cccc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)n1C(COC)COC |r|
Show InChI InChI=1S/C23H32ClN7O7S/c1-15(20(37-5)21-25-11-16(24)12-26-21)39(32,33)30-23-29-28-22(31(23)17(13-35-3)14-36-4)18-7-6-8-19(27-18)38-10-9-34-2/h6-8,11-12,15,17,20H,9-10,13-14H2,1-5H3,(H,29,30)/t15-,20-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447712
PNG
(US10689367, Example 43.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1CCOC(F)F)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C19H22ClF2N7O5S/c1-11(15(33-3)16-23-9-12(20)10-24-16)35(30,31)28-19-27-26-17(29(19)7-8-34-18(21)22)13-5-4-6-14(25-13)32-2/h4-6,9-11,15,18H,7-8H2,1-3H3,(H,27,28)/t11-,15-/m0/s1
PDB

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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447714
PNG
(US10689367, Example 44.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1CCC#N)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C19H21ClN8O4S/c1-12(16(32-3)17-22-10-13(20)11-23-17)33(29,30)27-19-26-25-18(28(19)9-5-8-21)14-6-4-7-15(24-14)31-2/h4,6-7,10-12,16H,5,9H2,1-3H3,(H,26,27)/t12-,16-/m0/s1
PDB

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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447715
PNG
(US10689367, Example 45.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1CCC(N)=O)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C19H23ClN8O5S/c1-11(16(33-3)17-22-9-12(20)10-23-17)34(30,31)27-19-26-25-18(28(19)8-7-14(21)29)13-5-4-6-15(24-13)32-2/h4-6,9-11,16H,7-8H2,1-3H3,(H2,21,29)(H,26,27)/t11-,16-/m0/s1
PDB

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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447721
PNG
(US10689367, Example 46.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2ccccn2)n1C(C1CC1)C1CC1)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C22H26ClN7O3S/c1-13(19(33-2)20-25-11-16(23)12-26-20)34(31,32)29-22-28-27-21(17-5-3-4-10-24-17)30(22)18(14-6-7-14)15-8-9-15/h3-5,10-15,18-19H,6-9H2,1-2H3,(H,28,29)/t13-,19-/m0/s1
PDB

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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447724
PNG
(US10689367, Example 47.0)
Show SMILES CCC(CC)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C20H26ClN7O3S/c1-5-15(6-2)28-19(16-9-7-8-10-22-16)25-26-20(28)27-32(29,30)13(3)17(31-4)18-23-11-14(21)12-24-18/h7-13,15,17H,5-6H2,1-4H3,(H,26,27)/t13-,17-/m0/s1
PDB

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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447725
PNG
(US10689367, Example 48.0)
Show SMILES COC[C@H](C)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C20H26ClN7O5S/c1-12(11-31-3)28-19(15-7-6-8-16(24-15)32-4)25-26-20(28)27-34(29,30)13(2)17(33-5)18-22-9-14(21)10-23-18/h6-10,12-13,17H,11H2,1-5H3,(H,26,27)/t12-,13-,17-/m0/s1
PDB

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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447726
PNG
(US10689367, Example 49.0)
Show SMILES COC[C@@H](C)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C20H26ClN7O5S/c1-12(11-31-3)28-19(15-7-6-8-16(24-15)32-4)25-26-20(28)27-34(29,30)13(2)17(33-5)18-22-9-14(21)10-23-18/h6-10,12-13,17H,11H2,1-5H3,(H,26,27)/t12-,13+,17+/m1/s1
PDB

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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447727
PNG
(US10689367, Example 50.0)
Show SMILES COCC1(CCC1)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C22H28ClN7O5S/c1-14(18(35-4)19-24-11-15(23)12-25-19)36(31,32)29-21-28-27-20(16-7-5-8-17(26-16)34-3)30(21)22(13-33-2)9-6-10-22/h5,7-8,11-12,14,18H,6,9-10,13H2,1-4H3,(H,28,29)/t14-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447728
PNG
(US10689367, Example 51.0)
Show SMILES COCC1(CCC1)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C21H26ClN7O4S/c1-14(17(33-3)18-24-11-15(22)12-25-18)34(30,31)28-20-27-26-19(16-7-4-5-10-23-16)29(20)21(13-32-2)8-6-9-21/h4-5,7,10-12,14,17H,6,8-9,13H2,1-3H3,(H,27,28)/t14-,17-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447729
PNG
(US10689367, Example 52.0 | US10689367, Example 53....)
Show SMILES COC[C@@H](C)n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)nnc1-c1cccnc1 |r|
Show InChI InChI=1S/C19H24ClN7O3S/c1-12(11-30-4)27-18(15-6-5-7-21-8-15)24-25-19(27)26-31(28,29)14(3)13(2)17-22-9-16(20)10-23-17/h5-10,12-14H,11H2,1-4H3,(H,25,26)/t12-,13+,14+/m1/s1
PDB

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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447729
PNG
(US10689367, Example 52.0 | US10689367, Example 53....)
Show SMILES COC[C@@H](C)n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)nnc1-c1cccnc1 |r|
Show InChI InChI=1S/C19H24ClN7O3S/c1-12(11-30-4)27-18(15-6-5-7-21-8-15)24-25-19(27)26-31(28,29)14(3)13(2)17-22-9-16(20)10-23-17/h5-10,12-14H,11H2,1-4H3,(H,25,26)/t12-,13+,14+/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447734
PNG
(US10689367, Example 54.0 | US10689367, Example 55....)
Show SMILES CC[C@@H](C)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C20H26ClN7O4S/c1-6-12(2)28-19(15-8-7-9-16(24-15)31-4)25-26-20(28)27-33(29,30)13(3)17(32-5)18-22-10-14(21)11-23-18/h7-13,17H,6H2,1-5H3,(H,26,27)/t12-,13+,17+/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447734
PNG
(US10689367, Example 54.0 | US10689367, Example 55....)
Show SMILES CC[C@@H](C)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C20H26ClN7O4S/c1-6-12(2)28-19(15-8-7-9-16(24-15)31-4)25-26-20(28)27-33(29,30)13(3)17(32-5)18-22-10-14(21)11-23-18/h7-13,17H,6H2,1-5H3,(H,26,27)/t12-,13+,17+/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447736
PNG
(US10689367, Example 56.0 | US10689367, Example 92....)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1[C@@H]1CCC11CCC1)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C23H28ClN7O4S/c1-14(19(35-3)20-25-12-15(24)13-26-20)36(32,33)30-22-29-28-21(16-6-4-7-18(27-16)34-2)31(22)17-8-11-23(17)9-5-10-23/h4,6-7,12-14,17,19H,5,8-11H2,1-3H3,(H,29,30)/t14-,17+,19-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447738
PNG
(US10689367, Example 57.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1CCS(C)(=O)=O)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C19H24ClN7O6S2/c1-12(16(33-3)17-21-10-13(20)11-22-17)35(30,31)26-19-25-24-18(27(19)8-9-34(4,28)29)14-6-5-7-15(23-14)32-2/h5-7,10-12,16H,8-9H2,1-4H3,(H,25,26)/t12-,16-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447739
PNG
(US10689367, Example 58.0)
Show SMILES CC(C)O[C@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cncc(C)c2)n1C1(C)CC1)c1ncc(C)cn1 |r|
Show InChI InChI=1S/C23H31N7O3S/c1-14(2)33-19(20-25-11-16(4)12-26-20)17(5)34(31,32)29-22-28-27-21(30(22)23(6)7-8-23)18-9-15(3)10-24-13-18/h9-14,17,19H,7-8H2,1-6H3,(H,28,29)/t17-,19+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447740
PNG
(US10689367, Example 59.0)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(C)n2)n1C1(C)CCC1)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C21H26ClN7O3S/c1-13-7-5-8-16(25-13)19-26-27-20(29(19)21(3)9-6-10-21)28-33(30,31)14(2)17(32-4)18-23-11-15(22)12-24-18/h5,7-8,11-12,14,17H,6,9-10H2,1-4H3,(H,27,28)/t14-,17-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447741
PNG
(US10689367, Example 60.0)
Show SMILES COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccnc1 |r|
Show InChI InChI=1S/C20H24ClN7O4S/c1-13(16(32-3)17-23-10-15(21)11-24-17)33(29,30)27-19-26-25-18(14-5-4-8-22-9-14)28(19)20(6-7-20)12-31-2/h4-5,8-11,13,16H,6-7,12H2,1-3H3,(H,26,27)/t13-,16-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447742
PNG
(US10689367, Example 61.0)
Show SMILES COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C20H24ClN7O4S/c1-13(16(32-3)17-23-10-14(21)11-24-17)33(29,30)27-19-26-25-18(15-6-4-5-9-22-15)28(19)20(7-8-20)12-31-2/h4-6,9-11,13,16H,7-8,12H2,1-3H3,(H,26,27)/t13-,16-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447743
PNG
(US10689367, Example 62.0)
Show SMILES COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)nnc1-c1cccnc1 |r|
Show InChI InChI=1S/C23H31N7O4S/c1-15(2)34-19(20-25-11-16(3)12-26-20)17(4)35(31,32)29-22-28-27-21(18-7-6-10-24-13-18)30(22)23(8-9-23)14-33-5/h6-7,10-13,15,17,19H,8-9,14H2,1-5H3,(H,28,29)/t17-,19+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447744
PNG
(US10689367, Example 63.0)
Show SMILES COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)nnc1-c1cncc(C)c1 |r|
Show InChI InChI=1S/C24H33N7O4S/c1-15(2)35-20(21-26-11-17(4)12-27-21)18(5)36(32,33)30-23-29-28-22(19-9-16(3)10-25-13-19)31(23)24(7-8-24)14-34-6/h9-13,15,18,20H,7-8,14H2,1-6H3,(H,29,30)/t18-,20+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447745
PNG
(US10689367, Example 64.0)
Show SMILES COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C24H33N7O5S/c1-15(2)36-20(21-25-12-16(3)13-26-21)17(4)37(32,33)30-23-29-28-22(18-8-7-9-19(27-18)35-6)31(23)24(10-11-24)14-34-5/h7-9,12-13,15,17,20H,10-11,14H2,1-6H3,(H,29,30)/t17-,20+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens (Human))		BDBM447746
PNG
(US10689367, Example 65.0)
Show SMILES COCC1(CC1)n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)nnc1-c1ccccn1 |r|
Show InChI InChI=1S/C23H31N7O4S/c1-15(2)34-19(20-25-12-16(3)13-26-20)17(4)35(31,32)29-22-28-27-21(18-8-6-7-11-24-18)30(22)23(9-10-23)14-33-5/h6-8,11-13,15,17,19H,9-10,14H2,1-5H3,(H,28,29)/t17-,19+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair
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