Compile Data Set for Download or QSAR

Found 98 hits Enz. Inhib. hit(s) with all data for entry = 9194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM448394 (1-[(6-{5-Azaspiro[2.3]hexan-5-yl}-2-methylpyridin-...) Show SMILES COCc1nn(Cc2ccc(nc2C)N2CC3(CC3)C2)cc1C(=O)N[C@@H]1CCc2c(C)n[nH]c12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448384 (7-[(6-{6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl}...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2C)N2CC3C(C2)C3(F)F)c2ncncc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448386 (1-[(6-{6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl}...) Show SMILES COCc1nn(Cc2ccc(nc2C)N2CC3C(C2)C3(F)F)cc1C(=O)N[C@@H]1CCc2c(C)n[nH]c12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448385 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2C)N2CC3CC3C2)nc1C(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448387 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES COCc1nn(Cc2ccc(nc2C)N2CC3CC3C2)cc1C(=O)N[C@@H]1CCc2c(C)n[nH]c12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448390 (1-[(6-{6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl}...) Show SMILES Cc1nn(Cc2ccc(nc2C)N2CC3C(C2)C3(F)F)cc1C(=O)N[C@@H]1CCc2c(C)n[nH]c12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448393 (7-[(2-{6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl}...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2cnc(nc2C)N2CC3C(C2)C3(F)F)c2ncncc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448388 (7-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2C)N2CC3CC3C2)c2ncncc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448392 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES COc1nn(Cc2ccc(nc2C)N2CC3CC3C2)cc1C(=O)N[C@@H]1CCc2c(C)n[nH]c12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448395 (7-[(2-{3-Azabicyclo[3.1.0]hexan-3-yl}-4-methyl- | ...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2cnc(nc2C)N2CC3CC3C2)c2ncncc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448377 (1-[(6-{6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl}...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC3C(C2)C3(F)F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448391 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES Cc1nn(Cc2ccc(nc2C)N2CC3CC3C2)cc1C(=O)N[C@@H]1CCc2c(C)n[nH]c12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448382 (1-[(6-{5-azaspiro[2.3]hexan-5-yl}-2-methylpyridin-...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC3(CC3)C2)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448400 (N-[(6R)-3-Methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-...) Show SMILES C[C@@H]1[C@@H]2CN(C[C@H]12)c1ccc(Cn2cc(cn2)C(=O)N[C@@H]2CCc3c(C)[nH]nc23)c(C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448376 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC3CC3C2)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448378 (4-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cc(Cc2ccc(nc2C)N2CC3CC3C2)cs1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448379 (4-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1nc(ccc1Cc1cc(C(O)=O)n(COCC[Si](C)(C)C)c1)N1CC2CC2C1 Show InChI InChI=1S/C23H33N3O3Si/c1-16-18(5-6-22(24-16)25-13-19-11-20(19)14-25)9-17-10-21(23(27)28)26(12-17)15-29-7-8-30(2,3)4/h5-6,10,12,19-20H,7-9,11,13-15H2,1-4H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448411 (N-[(6R)-3-Methyl-2H,4H,5H,6H-cyclopenta[c]- | US10...) Show SMILES C[C@@H]1[C@@H]2CN(C[C@H]12)c1ccc(Cn2cnc(c2)C(=O)N[C@@H]2CCc3c(C)[nH]nc23)c(C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448396 (1{[6-(3,3-Dimethylpyrrolidin-1-yl)-2-methylpyridin...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CCC(C)(C)C2)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448320 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1n[nH]c2C(CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC3CC3C2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448410 (1-({6-[(1R,5S,6S)-6-(Hydroxymethyl)-3-aza- | US106...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cn(Cc2c(C)cc(nc2C)N2C[C@H]3[C@@H](CO)[C@H]3C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448408 (1-[(6-(3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES Cc1nc(cn1Cc1ccc(nc1C)N1CC2CC2C1)C(=O)NC1CCc2c(C)[nH]nc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448407 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2C)N2CC3CC3C2)c(n1)C1CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448406 (1-[(2-{3-Azabicyclo[3.1.0]hexan-3-yl}-4-methylpyri...) Show SMILES Cc1c2CC[C@@H](NC(=O)c3cn(Cc4cnc(nc4C)N4CC5CC5C4)nn3)c2nn1COCC[Si](C)(C)C |r| Show InChI InChI=1S/C27H39N9O2Si/c1-17-21(11-28-27(29-17)34-12-19-10-20(19)13-34)14-35-15-24(31-33-35)26(37)30-23-7-6-22-18(2)36(32-25(22)23)16-38-8-9-39(3,4)5/h11,15,19-20,23H,6-10,12-14,16H2,1-5H3,(H,30,37)/t19?,20?,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448404 (1-{[6-(3-Cyano-3-methylpyrrolidin-1-yl)-2-methylpy...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CCC(C)(C2)C#N)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448403 (1-{[6-(3,3-Dimethylazetidin-1-yl)-2-methylpyridin-...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC(C)(C)C2)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448401 (N-[(6R)-3-Methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CCCC2)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448402 (1-[(6-{2-Azaspiro[3.31]heptan-2-yl}-2-methylpyridi...) Show SMILES Cc1c2CC[C@@H](NC(=O)c3cnn(Cc4ccc(F)nc4C)c3)c2nn1COCC[Si](C)(C)C |r| Show InChI InChI=1S/C24H33FN6O2Si/c1-16-18(6-9-22(25)27-16)13-30-14-19(12-26-30)24(32)28-21-8-7-20-17(2)31(29-23(20)21)15-33-10-11-34(3,4)5/h6,9,12,14,21H,7-8,10-11,13,15H2,1-5H3,(H,28,32)/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448416 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-cyano- | U...) Show SMILES Cc1[nH]nc2C(CCc12)NC(=O)c1cn(Cc2ccc(nc2C#N)N2CC3CC3C2)cn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448399 (1-({6-[3-(Difluoromethyl)pyrrolidin-1-yl]-2-methyl...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CCC(C2)C(F)F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448397 (1-[(6-{6-Azaspiro[3.4]octan-6-yl}-2-methylpyridin-...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CCC3(CCC3)C2)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448412 (1-({4-Methyl-2-[(1R,5S,6R)-6-methyl-3- | US1069533...) Show SMILES C[C@@H]1[C@@H]2CN(C[C@H]12)c1ncc(Cn2cnc(c2)C(=O)N[C@@H]2CCc3c(C)[nH]nc23)c(C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448383 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2C)N2CC3CC3C2)nc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448398 (1-{[6-(3,3-Difluoropyrrolidin-1-yl)-2-methylpyridi...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CCC(F)(F)C2)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448414 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}pyridin-3-yl)...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2)N2CC3CC3C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448415 (1-[(6-{5-Azaspiro[2.3]hexan-5-yl}pyridin-3-yl)- | ...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2)N2CC3(CC3)C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448380 (4-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cc(Cc2ccc(nc2C)N2CC3CC3C2)c(s1)C#N |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448413 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2C)N2CC3CC3C2)c(Cl)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448405 (1-{[6-(3-Fluoro-3-methylazetidin-1-yl)-2-methylpyr...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC(C)(F)C2)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448381 (2-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1nnn(Cc2ccc(nc2C)N2CC3CC3C2)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448417 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES COC(=O)c1ccc2n(Cc3ccc(nc3C)N3CC4CC4C3)cc(C(=O)N[C@@H]3CCc4c(C)n(COCC[Si](C)(C)C)nc34)c2c1 |r| Show InChI InChI=1S/C36H46N6O4Si/c1-22-25(8-12-33(37-22)41-18-26-15-27(26)19-41)17-40-20-30(29-16-24(36(44)45-3)7-11-32(29)40)35(43)38-31-10-9-28-23(2)42(39-34(28)31)21-46-13-14-47(4,5)6/h7-8,11-12,16,20,26-27,31H,9-10,13-15,17-19,21H2,1-6H3,(H,38,43)/t26?,27?,31-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM448409 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(nc2C)N2CC3CC3C2)c(n1)C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM448376 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC3CC3C2)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM448320 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyri...) Show SMILES Cc1n[nH]c2C(CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC3CC3C2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM448377 (1-[(6-{6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl}...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC3C(C2)C3(F)F)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM448392 (1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methyl- | ...) Show SMILES COc1nn(Cc2ccc(nc2C)N2CC3CC3C2)cc1C(=O)N[C@@H]1CCc2c(C)n[nH]c12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM448393 (7-[(2-{6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl}...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2cnc(nc2C)N2CC3C(C2)C3(F)F)c2ncncc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM448394 (1-[(6-{5-Azaspiro[2.3]hexan-5-yl}-2-methylpyridin-...) Show SMILES COCc1nn(Cc2ccc(nc2C)N2CC3(CC3)C2)cc1C(=O)N[C@@H]1CCc2c(C)n[nH]c12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM448395 (7-[(2-{3-Azabicyclo[3.1.0]hexan-3-yl}-4-methyl- | ...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2cnc(nc2C)N2CC3CC3C2)c2ncncc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM448418 (1-[(2-{3-Azabicyclo[3.1.0]hexan-3-yl}-4-methyl- | ...) Show SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2cnc(nc2C)N2CC3CC3C2)nc1C |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...				US Patent US10695334 (2020) BindingDB Entry DOI: 10.7270/Q2VT1W4K
					More data for this Ligand-Target Pair

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