Compile Data Set for Download or QSAR

Found 378 hits Enz. Inhib. hit(s) with all data for entry = 9394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463582 (US10781204, Compound I-186 | US10781204, Compound ...) Show SMILES CC1(O)CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C23H21FN6O2/c1-23(32)7-3-8-29(13-23)19-6-9-30(28-19)18-10-16(27-17-12-26-22(31)21(17)18)20-14(11-25)4-2-5-15(20)24/h2,4-6,9-10,32H,3,7-8,12-13H2,1H3,(H,26,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463752 (US10781204, Compound I-229 | US11434240, Compound ...) Show SMILES CO[C@H]1CCN(C[C@@]1(C)O)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C24H23FN6O3/c1-24(33)13-30(8-6-19(24)34-2)20-7-9-31(29-20)18-10-16(28-17-12-27-23(32)22(17)18)21-14(11-26)4-3-5-15(21)25/h3-5,7,9-10,19,33H,6,8,12-13H2,1-2H3,(H,27,32)/t19-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463596 (US10781204, Compound I-194 | US10781204, Compound ...) Show SMILES OC1CCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C21H17FN6O2/c22-14-3-1-2-12(9-23)19(14)15-8-17(20-16(25-15)10-24-21(20)30)28-7-5-18(26-28)27-6-4-13(29)11-27/h1-3,5,7-8,13,29H,4,6,10-11H2,(H,24,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463605 (US10781204, Compound I-84 | US11434240, Compound I...) Show SMILES NC1(CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N)C(F)(F)F Show InChI InChI=1S/C23H19F4N7O/c24-14-4-1-3-13(10-28)19(14)15-9-17(20-16(31-15)11-30-21(20)35)34-8-5-18(32-34)33-7-2-6-22(29,12-33)23(25,26)27/h1,3-5,8-9H,2,6-7,11-12,29H2,(H,30,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463609 (US10781204, Compound I-88 | US11434240, Compound I...) Show SMILES O[C@@]1(CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N)C(F)(F)F |r| Show InChI InChI=1S/C23H18F4N6O2/c24-14-4-1-3-13(10-28)19(14)15-9-17(20-16(30-15)11-29-21(20)34)33-8-5-18(31-33)32-7-2-6-22(35,12-32)23(25,26)27/h1,3-5,8-9,35H,2,6-7,11-12H2,(H,29,34)/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463621 (US10781204, Compound I-100 | US11434240, Compound ...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCC2(C1)OCCO2 Show InChI InChI=1S/C23H19FN6O3/c24-15-3-1-2-14(11-25)20(15)16-10-18(21-17(27-16)12-26-22(21)31)30-6-4-19(28-30)29-7-5-23(13-29)32-8-9-33-23/h1-4,6,10H,5,7-9,12-13H2,(H,26,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463639 (US10781204, Compound I-118 | US11434240, Compound ...) Show SMILES N[C@]1(CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N)C(F)(F)F |r| Show InChI InChI=1S/C23H19F4N7O/c24-14-4-1-3-13(10-28)19(14)15-9-17(20-16(31-15)11-30-21(20)35)34-8-5-18(32-34)33-7-2-6-22(29,12-33)23(25,26)27/h1,3-5,8-9H,2,6-7,11-12,29H2,(H,30,35)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463640 (US10781204, Compound I-119 | US11434240, Compound ...) Show SMILES N[C@@]1(CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N)C(F)(F)F |r| Show InChI InChI=1S/C23H19F4N7O/c24-14-4-1-3-13(10-28)19(14)15-9-17(20-16(31-15)11-30-21(20)35)34-8-5-18(32-34)33-7-2-6-22(29,12-33)23(25,26)27/h1,3-5,8-9H,2,6-7,11-12,29H2,(H,30,35)/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463657 (US10781204, Compound I-136 | US11434240, Compound ...) Show SMILES O[C@H]1CCN(C[C@H]1O)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H19FN6O3/c23-13-3-1-2-12(9-24)20(13)14-8-16(21-15(26-14)10-25-22(21)32)29-7-5-19(27-29)28-6-4-17(30)18(31)11-28/h1-3,5,7-8,17-18,30-31H,4,6,10-11H2,(H,25,32)/t17-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463662 (US10781204, Compound I-141 | US11434240, Compound ...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCNC(=O)CC1 Show InChI InChI=1S/C22H18FN7O2/c23-14-3-1-2-13(11-24)20(14)15-10-17(21-16(27-15)12-26-22(21)32)30-8-4-18(28-30)29-7-5-19(31)25-6-9-29/h1-4,8,10H,5-7,9,12H2,(H,25,31)(H,26,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463600 (US10781204, Compound I-142 | US10781204, Compound ...) Show SMILES O[C@H]1CCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C21H17FN6O2/c22-14-3-1-2-12(9-23)19(14)15-8-17(20-16(25-15)10-24-21(20)30)28-7-5-18(26-28)27-6-4-13(29)11-27/h1-3,5,7-8,13,29H,4,6,10-11H2,(H,24,30)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463671 (US10781204, Compound I-149 | US11434240, Compound ...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCCC(C1)N1CCOCC1 Show InChI InChI=1S/C26H26FN7O2/c27-19-5-1-3-17(14-28)24(19)20-13-22(25-21(30-20)15-29-26(25)35)34-8-6-23(31-34)33-7-2-4-18(16-33)32-9-11-36-12-10-32/h1,3,5-6,8,13,18H,2,4,7,9-12,15-16H2,(H,29,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463672 (US10781204, Compound I-150 | US11434240, Compound ...) Show SMILES C[C@H]1[C@H](O)CCN1c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H19FN6O2/c1-12-18(30)5-7-28(12)19-6-8-29(27-19)17-9-15(26-16-11-25-22(31)21(16)17)20-13(10-24)3-2-4-14(20)23/h2-4,6,8-9,12,18,30H,5,7,11H2,1H3,(H,25,31)/t12-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463682 (US10781204, Compound I-160 | US11434240, Compound ...) Show SMILES OC1CN(CCC1F)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C22H18F2N6O2/c23-13-4-6-29(11-18(13)31)19-5-7-30(28-19)17-8-15(27-16-10-26-22(32)21(16)17)20-12(9-25)2-1-3-14(20)24/h1-3,5,7-8,13,18,31H,4,6,10-11H2,(H,26,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463684 (US10781204, Compound I-162 | US11434240, Compound ...) Show SMILES C[C@]1(O)CN(CC[C@H]1O)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C23H21FN6O3/c1-23(33)12-29(7-5-18(23)31)19-6-8-30(28-19)17-9-15(27-16-11-26-22(32)21(16)17)20-13(10-25)3-2-4-14(20)24/h2-4,6,8-9,18,31,33H,5,7,11-12H2,1H3,(H,26,32)/t18-,23+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463689 (US10781204, Compound I-166 | US11434240, Compound ...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CC[C@@]2(CCNC2=O)C1 |r| Show InChI InChI=1S/C24H20FN7O2/c25-15-3-1-2-14(11-26)20(15)16-10-18(21-17(29-16)12-28-22(21)33)32-8-4-19(30-32)31-9-6-24(13-31)5-7-27-23(24)34/h1-4,8,10H,5-7,9,12-13H2,(H,27,34)(H,28,33)/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463696 (US10781204, Compound I-173 | US11434240, Compound ...) Show SMILES O[C@H]1CN(CC[C@H]1F)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H18F2N6O2/c23-13-4-6-29(11-18(13)31)19-5-7-30(28-19)17-8-15(27-16-10-26-22(32)21(16)17)20-12(9-25)2-1-3-14(20)24/h1-3,5,7-8,13,18,31H,4,6,10-11H2,(H,26,32)/t13-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463710 (US10781204, Compound I-187 | US11434240, Compound ...) Show SMILES CC1(C)C(O)CCN1c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C23H21FN6O2/c1-23(2)18(31)6-8-29(23)19-7-9-30(28-19)17-10-15(27-16-12-26-22(32)21(16)17)20-13(11-25)4-3-5-14(20)24/h3-5,7,9-10,18,31H,6,8,12H2,1-2H3,(H,26,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463711 (US10781204, Compound I-188 | US11434240, Compound ...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1C[C@@H]2CC[C@H](C1)O2 |r| Show InChI InChI=1S/C23H19FN6O2/c24-16-3-1-2-13(9-25)21(16)17-8-19(22-18(27-17)10-26-23(22)31)30-7-6-20(28-30)29-11-14-4-5-15(12-29)32-14/h1-3,6-8,14-15H,4-5,10-12H2,(H,26,31)/t14-,15+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463736 (US10781204, Compound I-213 | US10781204, Compound ...) Show SMILES CO[C@@H]1CCN(C[C@]1(C)O)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C24H23FN6O3/c1-24(33)13-30(8-6-19(24)34-2)20-7-9-31(29-20)18-10-16(28-17-12-27-23(32)22(17)18)21-14(11-26)4-3-5-15(21)25/h3-5,7,9-10,19,33H,6,8,12-13H2,1-2H3,(H,27,32)/t19-,24+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463591 (US10781204, Compound I-111 | US10781204, Compound ...) Show SMILES C[C@@]1(O)CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C23H21FN6O2/c1-23(32)7-3-8-29(13-23)19-6-9-30(28-19)18-10-16(27-17-12-26-22(31)21(17)18)20-14(11-25)4-2-5-15(20)24/h2,4-6,9-10,32H,3,7-8,12-13H2,1H3,(H,26,31)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463567 (US10781204, Compound I-1 | US11434240, Compound I-...) Show SMILES Fc1cccc(F)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCOCC1 Show InChI InChI=1S/C20H17F2N5O2/c21-12-2-1-3-13(22)18(12)14-10-16(19-15(24-14)11-23-20(19)28)27-5-4-17(25-27)26-6-8-29-9-7-26/h1-5,10H,6-9,11H2,(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463569 (US10781204, Compound I-3 | US11434240, Compound I-...) Show SMILES CCNC(=O)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1F Show InChI InChI=1S/C19H15F2N5O2/c1-2-22-18(27)12-6-7-26(25-12)15-8-13(16-10(20)4-3-5-11(16)21)24-14-9-23-19(28)17(14)15/h3-8H,2,9H2,1H3,(H,22,27)(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463570 (US10781204, Compound I-4 | US11434240, Compound I-...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCOCC1 Show InChI InChI=1S/C21H17FN6O2/c22-14-3-1-2-13(11-23)19(14)15-10-17(20-16(25-15)12-24-21(20)29)28-5-4-18(26-28)27-6-8-30-9-7-27/h1-5,10H,6-9,12H2,(H,24,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463571 (US10781204, Compound I-5 | US11434240, Compound I-...) Show SMILES CN1CCN(CC1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1F Show InChI InChI=1S/C21H20F2N6O/c1-27-7-9-28(10-8-27)18-5-6-29(26-18)17-11-15(19-13(22)3-2-4-14(19)23)25-16-12-24-21(30)20(16)17/h2-6,11H,7-10,12H2,1H3,(H,24,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463572 (US10781204, Compound I-6 | US11434240, Compound I-...) Show SMILES CN1CCN(CC1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C22H20FN7O/c1-28-7-9-29(10-8-28)19-5-6-30(27-19)18-11-16(26-17-13-25-22(31)21(17)18)20-14(12-24)3-2-4-15(20)23/h2-6,11H,7-10,13H2,1H3,(H,25,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM463572 (US10781204, Compound I-6 | US11434240, Compound I-...) Show SMILES CN1CCN(CC1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C22H20FN7O/c1-28-7-9-29(10-8-28)19-5-6-30(27-19)18-11-16(26-17-13-25-22(31)21(17)18)20-14(12-24)3-2-4-15(20)23/h2-6,11H,7-10,13H2,1H3,(H,25,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463573 (US10781204, Compound I-7 | US11434240, Compound I-...) Show SMILES CCNC(=O)Cc1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C21H17FN6O2/c1-2-24-18(29)8-13-6-7-28(27-13)17-9-15(26-16-11-25-21(30)20(16)17)19-12(10-23)4-3-5-14(19)22/h3-7,9H,2,8,11H2,1H3,(H,24,29)(H,25,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463574 (US10781204, Compound I-9 | US11434240, Compound I-...) Show SMILES Fc1cccc(F)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCC2(CCOCC2)CC1 Show InChI InChI=1S/C25H25F2N5O2/c26-16-2-1-3-17(27)22(16)18-14-20(23-19(29-18)15-28-24(23)33)32-9-4-21(30-32)31-10-5-25(6-11-31)7-12-34-13-8-25/h1-4,9,14H,5-8,10-13,15H2,(H,28,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463575 (US10781204, Compound I-16 | US11434240, Compound I...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)C1CCOCC1 Show InChI InChI=1S/C22H18FN5O2/c23-15-3-1-2-14(11-24)20(15)17-10-19(21-18(26-17)12-25-22(21)29)28-7-4-16(27-28)13-5-8-30-9-6-13/h1-4,7,10,13H,5-6,8-9,12H2,(H,25,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463576 (US10781204, Compound I-203 | US10781204, Compound ...) Show SMILES OC1CCN(CC1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C22H19FN6O2/c23-15-3-1-2-13(11-24)20(15)16-10-18(21-17(26-16)12-25-22(21)31)29-9-6-19(27-29)28-7-4-14(30)5-8-28/h1-3,6,9-10,14,30H,4-5,7-8,12H2,(H,25,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463577 (US10781204, Compound I-57 | US11434240, Compound I...) Show SMILES CC(C)n1ccc(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C20H16FN5O/c1-11(2)26-7-6-15(25-26)13-8-16(24-17-10-23-20(27)19(13)17)18-12(9-22)4-3-5-14(18)21/h3-8,11H,10H2,1-2H3,(H,23,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463579 (US10781204, Compound I-59) Show SMILES Fc1cccc(Cl)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C25H26ClFN6O2/c26-17-2-1-3-18(27)23(17)19-14-21(24-20(29-19)15-28-25(24)34)33-9-6-22(30-33)32-7-4-16(5-8-32)31-10-12-35-13-11-31/h1-3,6,9,14,16H,4-5,7-8,10-13,15H2,(H,28,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM463579 (US10781204, Compound I-59) Show SMILES Fc1cccc(Cl)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C25H26ClFN6O2/c26-17-2-1-3-18(27)23(17)19-14-21(24-20(29-19)15-28-25(24)34)33-9-6-22(30-33)32-7-4-16(5-8-32)31-10-12-35-13-11-31/h1-3,6,9,14,16H,4-5,7-8,10-13,15H2,(H,28,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463580 (US10781204, Compound I-60 | US11434240, Compound I...) Show SMILES CC1(C)COC(=N1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |c:5| Show InChI InChI=1S/C22H17FN6O2/c1-22(2)11-31-21(27-22)14-6-7-29(28-14)17-8-15(26-16-10-25-20(30)19(16)17)18-12(9-24)4-3-5-13(18)23/h3-8H,10-11H2,1-2H3,(H,25,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463581 (US10781204, Compound I-61 | US11434240, Compound I...) Show SMILES CC(C)n1cc(cn1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C20H16FN5O/c1-11(2)26-10-13(8-24-26)14-6-16(25-17-9-23-20(27)19(14)17)18-12(7-22)4-3-5-15(18)21/h3-6,8,10-11H,9H2,1-2H3,(H,23,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463583 (US10781204, Compound I-63 | US11434240, Compound I...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(NCCN2CCOCC2)n1 Show InChI InChI=1S/C23H22FN7O2/c24-16-3-1-2-15(13-25)21(16)17-12-19(22-18(28-17)14-27-23(22)32)31-6-4-20(29-31)26-5-7-30-8-10-33-11-9-30/h1-4,6,12H,5,7-11,14H2,(H,26,29)(H,27,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463584 (US10781204, Compound I-64 | US11434240, Compound I...) Show SMILES OCCNc1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C19H15FN6O2/c20-12-3-1-2-11(9-21)17(12)13-8-15(18-14(24-13)10-23-19(18)28)26-6-4-16(25-26)22-5-7-27/h1-4,6,8,27H,5,7,10H2,(H,22,25)(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463585 (US10781204, Compound I-65 | US11434240, Compound I...) Show SMILES OC1CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C22H19FN6O2/c23-15-5-1-3-13(10-24)20(15)16-9-18(21-17(26-16)11-25-22(21)31)29-8-6-19(27-29)28-7-2-4-14(30)12-28/h1,3,5-6,8-9,14,30H,2,4,7,11-12H2,(H,25,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463586 (US10781204, Compound I-66 | US11434240, Compound I...) Show SMILES Fc1cccc(C#N)c1-c1cc(c2C(=O)NCc2n1)-n1ccc(n1)N1CCC(CC1)N1CCCC1 Show InChI InChI=1S/C26H26FN7O/c27-19-5-3-4-17(15-28)24(19)20-14-22(25-21(30-20)16-29-26(25)35)34-13-8-23(31-34)33-11-6-18(7-12-33)32-9-1-2-10-32/h3-5,8,13-14,18H,1-2,6-7,9-12,16H2,(H,29,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463587 (US10781204, Compound I-67 | US11434240, Compound I...) Show SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r,wU:3.2,wD:6.9,(-5.32,-3.79,;-6.09,-2.45,;-7.63,-2.45,;-5.32,-1.12,;-6.09,.21,;-5.32,1.55,;-3.78,1.55,;-3.01,.21,;-3.78,-1.12,;-3.01,2.88,;-1.48,3.04,;-.71,4.38,;.8,4.06,;.96,2.52,;-.45,1.9,;2.29,1.75,;2.29,.21,;3.63,-.56,;4.96,.21,;4.96,1.75,;6.11,2.79,;5.48,4.19,;3.95,4.03,;2.92,5.18,;3.63,2.52,;3.63,-2.1,;2.29,-2.87,;.96,-2.1,;2.29,-4.41,;3.63,-5.18,;4.96,-4.41,;5.01,-2.84,;6.34,-2.07,;7.68,-1.3,)| Show InChI InChI=1S/C25H26FN7O/c1-32(2)17-8-6-16(7-9-17)29-22-10-11-33(31-22)21-12-19(30-20-14-28-25(34)24(20)21)23-15(13-27)4-3-5-18(23)26/h3-5,10-12,16-17H,6-9,14H2,1-2H3,(H,28,34)(H,29,31)/t16-,17-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463588 (US10781204, Compound I-68 | US11434240, Compound I...) Show SMILES NC1CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N Show InChI InChI=1S/C22H20FN7O/c23-15-5-1-3-13(10-24)20(15)16-9-18(21-17(27-16)11-26-22(21)31)30-8-6-19(28-30)29-7-2-4-14(25)12-29/h1,3,5-6,8-9,14H,2,4,7,11-12,25H2,(H,26,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463589 (US10781204, Compound I-69 | US11434240, Compound I...) Show SMILES O[C@@H]1CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H19FN6O2/c23-15-5-1-3-13(10-24)20(15)16-9-18(21-17(26-16)11-25-22(21)31)29-8-6-19(27-29)28-7-2-4-14(30)12-28/h1,3,5-6,8-9,14,30H,2,4,7,11-12H2,(H,25,31)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463590 (US10781204, Compound I-70 | US11434240, Compound I...) Show SMILES O[C@H]1CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H19FN6O2/c23-15-5-1-3-13(10-24)20(15)16-9-18(21-17(26-16)11-25-22(21)31)29-8-6-19(27-29)28-7-2-4-14(30)12-28/h1,3,5-6,8-9,14,30H,2,4,7,11-12H2,(H,25,31)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM463590 (US10781204, Compound I-70 | US11434240, Compound I...) Show SMILES O[C@H]1CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H19FN6O2/c23-15-5-1-3-13(10-24)20(15)16-9-18(21-17(26-16)11-25-22(21)31)29-8-6-19(27-29)28-7-2-4-14(30)12-28/h1,3,5-6,8-9,14,30H,2,4,7,11-12H2,(H,25,31)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463592 (US10781204, Compound I-72 | US11434240, Compound I...) Show SMILES C[C@]1(O)CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C23H21FN6O2/c1-23(32)7-3-8-29(13-23)19-6-9-30(28-19)18-10-16(27-17-12-26-22(31)21(17)18)20-14(11-25)4-2-5-15(20)24/h2,4-6,9-10,32H,3,7-8,12-13H2,1H3,(H,26,31)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM463592 (US10781204, Compound I-72 | US11434240, Compound I...) Show SMILES C[C@]1(O)CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C23H21FN6O2/c1-23(32)7-3-8-29(13-23)19-6-9-30(28-19)18-10-16(27-17-12-26-22(31)21(17)18)20-14(11-25)4-2-5-15(20)24/h2,4-6,9-10,32H,3,7-8,12-13H2,1H3,(H,26,31)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463593 (US10781204, Compound I-73 | US11434240, Compound I...) Show SMILES N[C@@H]1CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H20FN7O/c23-15-5-1-3-13(10-24)20(15)16-9-18(21-17(27-16)11-26-22(21)31)30-8-6-19(28-30)29-7-2-4-14(25)12-29/h1,3,5-6,8-9,14H,2,4,7,11-12,25H2,(H,26,31)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM463593 (US10781204, Compound I-73 | US11434240, Compound I...) Show SMILES N[C@@H]1CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H20FN7O/c23-15-5-1-3-13(10-24)20(15)16-9-18(21-17(27-16)11-26-22(21)31)30-8-6-19(28-30)29-7-2-4-14(25)12-29/h1,3,5-6,8-9,14H,2,4,7,11-12,25H2,(H,26,31)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM463594 (US10781204, Compound I-74 | US11434240, Compound I...) Show SMILES N[C@H]1CCCN(C1)c1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C22H20FN7O/c23-15-5-1-3-13(10-24)20(15)16-9-18(21-17(27-16)11-26-22(21)31)30-8-6-19(28-30)29-7-2-4-14(25)12-29/h1,3,5-6,8-9,14H,2,4,7,11-12,25H2,(H,26,31)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10781204 (2020) BindingDB Entry DOI: 10.7270/Q21G0Q9G
					More data for this Ligand-Target Pair

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