Compile Data Set for Download or QSAR

Found 416 hits Enz. Inhib. hit(s) with all data for entry = 9698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death protein 1 (Homo sapiens)	BDBM482344 (US10919852, Compound TABLE 1.43) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCCCN2CC[C@H](O)C2)c(CN[C@@H]2CCCC[C@@H]2O)cc1Cl |r| Show InChI InChI=1S/C44H60ClN3O6/c1-30-34(8-5-13-41(30)52-24-6-19-47-21-16-32(49)17-22-47)35-9-4-10-37-36(35)14-15-42(37)54-44-27-43(53-25-7-20-48-23-18-33(50)29-48)31(26-38(44)45)28-46-39-11-2-3-12-40(39)51/h4-5,8-10,13,26-27,32-33,39-40,42,46,49-51H,2-3,6-7,11-12,14-25,28-29H2,1H3/t33-,39+,40-,42-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482345 (US10919852, Compound TABLE 1.44 | US11708326, Comp...) Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC(O)C3)c2C)c(Cl)cc1CN[C@@H](CO)C(O)=O |r| Show InChI InChI=1S/C34H41ClN2O7/c1-3-42-32-16-33(28(35)15-22(32)17-36-29(20-38)34(40)41)44-31-12-11-26-25(8-4-9-27(26)31)24-7-5-10-30(21(24)2)43-14-6-13-37-18-23(39)19-37/h4-5,7-10,15-16,23,29,31,36,38-39H,3,6,11-14,17-20H2,1-2H3,(H,40,41)/t29-,31-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482346 (US10919852, Compound TABLE 1.45 | US11708326, Comp...) Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(F)CC3)c2C)c(Cl)cc1CN[C@@H](CO)C(O)=O |r| Show InChI InChI=1S/C36H44ClFN2O6/c1-3-44-34-20-35(30(37)19-24(34)21-39-31(22-41)36(42)43)46-33-12-11-28-27(8-4-9-29(28)33)26-7-5-10-32(23(26)2)45-18-6-15-40-16-13-25(38)14-17-40/h4-5,7-10,19-20,25,31,33,39,41H,3,6,11-18,21-22H2,1-2H3,(H,42,43)/t31-,33-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482347 (US10919852, Compound TABLE 1.46 | US11708326, Comp...) Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC4(CC(O)C4)C3)c2C)c(Cl)cc1CN[C@@H](CO)C(O)=O |r| Show InChI InChI=1S/C37H45ClN2O7/c1-3-45-34-16-35(30(38)15-24(34)19-39-31(20-41)36(43)44)47-33-12-11-28-27(8-4-9-29(28)33)26-7-5-10-32(23(26)2)46-14-6-13-40-21-37(22-40)17-25(42)18-37/h4-5,7-10,15-16,25,31,33,39,41-42H,3,6,11-14,17-22H2,1-2H3,(H,43,44)/t31-,33-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482352 (US10919852, Compound TABLE 1.51 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)cc1OCc1cncc(c1)C#N)C(N)=O |r| Show InChI InChI=1S/C42H48ClN5O6/c1-26-32(6-4-9-37(26)52-17-5-14-48-15-12-31(50)13-16-48)33-7-3-8-35-34(33)10-11-38(35)54-40-20-39(53-25-29-18-28(21-44)22-46-23-29)30(19-36(40)43)24-47-41(27(2)49)42(45)51/h3-4,6-9,18-20,22-23,27,31,38,41,47,49-50H,5,10-17,24-25H2,1-2H3,(H2,45,51)/t27-,38+,41+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482353 (US10919852, Compound TABLE 1.52 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H](CO)C(N)=O)cc1Cl |r| Show InChI InChI=1S/C41H46ClN5O6/c1-26-31(5-3-8-37(26)51-16-4-13-47-14-11-30(49)12-15-47)32-6-2-7-34-33(32)9-10-38(34)53-40-19-39(52-25-28-17-27(20-43)21-45-22-28)29(18-35(40)42)23-46-36(24-48)41(44)50/h2-3,5-8,17-19,21-22,30,36,38,46,48-49H,4,9-16,23-25H2,1H3,(H2,44,50)/t36-,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482354 (US10919852, Compound TABLE 1.53 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)cc1OCc1cncc(c1)C#N)C(=O)NS(C)(=O)=O |r| Show InChI InChI=1S/C43H50ClN5O8S/c1-27-33(7-5-10-38(27)55-18-6-15-49-16-13-32(51)14-17-49)34-8-4-9-36-35(34)11-12-39(36)57-41-21-40(56-26-30-19-29(22-45)23-46-24-30)31(20-37(41)44)25-47-42(28(2)50)43(52)48-58(3,53)54/h4-5,7-10,19-21,23-24,28,32,39,42,47,50-51H,6,11-18,25-26H2,1-3H3,(H,48,52)/t28-,39+,42+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482355 (US10919852, Compound TABLE 1.54 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CCC(O)CC2)cc1Cl |r| Show InChI InChI=1S/C43H49ClN4O5/c1-29-35(5-3-8-40(29)51-20-4-15-47-16-11-33(49)12-17-47)36-6-2-7-38-37(36)9-10-41(38)53-43-23-42(52-28-31-21-30(24-45)25-46-26-31)32(22-39(43)44)27-48-18-13-34(50)14-19-48/h2-3,5-8,21-23,25-26,33-34,41,49-50H,4,9-20,27-28H2,1H3/t41-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482356 (US10919852, Compound TABLE 1.55 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CC[C@H](O)C2)cc1Cl |r| Show InChI InChI=1S/C42H47ClN4O5/c1-28-34(5-3-8-39(28)50-18-4-14-46-15-11-32(48)12-16-46)35-6-2-7-37-36(35)9-10-40(37)52-42-21-41(51-27-30-19-29(22-44)23-45-24-30)31(20-38(42)43)25-47-17-13-33(49)26-47/h2-3,5-8,19-21,23-24,32-33,40,48-49H,4,9-18,25-27H2,1H3/t33-,40-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482357 (US10919852, Compound TABLE 1.56 | US11708326, Comp...) Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC[C@@H](O)C3)c2C)c(Cl)cc1CNC(CO)CO |r| Show InChI InChI=1S/C35H45ClN2O6/c1-3-42-34-18-35(31(36)17-24(34)19-37-25(21-39)22-40)44-33-12-11-29-28(8-4-9-30(29)33)27-7-5-10-32(23(27)2)43-16-6-14-38-15-13-26(41)20-38/h4-5,7-10,17-18,25-26,33,37,39-41H,3,6,11-16,19-22H2,1-2H3/t26-,33+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482358 (US10919852, Compound TABLE 1.57 | US11708326, Comp...) Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC[C@@H](O)C3)c2C)c(Cl)cc1CNC(C)(CO)CO |r| Show InChI InChI=1S/C36H47ClN2O6/c1-4-43-34-19-35(31(37)18-25(34)20-38-36(3,22-40)23-41)45-33-13-12-29-28(9-5-10-30(29)33)27-8-6-11-32(24(27)2)44-17-7-15-39-16-14-26(42)21-39/h5-6,8-11,18-19,26,33,38,40-42H,4,7,12-17,20-23H2,1-3H3/t26-,33+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482359 (US10919852, Compound TABLE 1.58 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CC[C@@H](O)C2)cc1Cl |r| Show InChI InChI=1S/C42H47ClN4O5/c1-28-34(5-3-8-39(28)50-18-4-14-46-15-11-32(48)12-16-46)35-6-2-7-37-36(35)9-10-40(37)52-42-21-41(51-27-30-19-29(22-44)23-45-24-30)31(20-38(42)43)25-47-17-13-33(49)26-47/h2-3,5-8,19-21,23-24,32-33,40,48-49H,4,9-18,25-27H2,1H3/t33-,40+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482360 (US10919852, Compound TABLE 1.59 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C43H48ClN5O5/c1-28-34(5-3-8-39(28)52-18-4-15-49-16-13-33(50)14-17-49)35-6-2-7-37-36(35)10-11-40(37)54-42-21-41(53-27-30-19-29(22-45)23-46-24-30)31(20-38(42)44)25-47-26-32-9-12-43(51)48-32/h2-3,5-8,19-21,23-24,32-33,40,47,50H,4,9-18,25-27H2,1H3,(H,48,51)/t32?,40-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482361 (US10919852, Compound TABLE 1.60 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC(C)(C)O)cc1Cl |r| Show InChI InChI=1S/C42H49ClN4O5/c1-28-33(7-5-10-38(28)50-18-6-15-47-16-13-32(48)14-17-47)34-8-4-9-36-35(34)11-12-39(36)52-41-21-40(51-26-30-19-29(22-44)23-45-24-30)31(20-37(41)43)25-46-27-42(2,3)49/h4-5,7-10,19-21,23-24,32,39,46,48-49H,6,11-18,25-27H2,1-3H3/t39-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482362 (US10919852, Compound TABLE 1.61 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CC(C2)C(O)=O)cc1Cl |r| Show InChI InChI=1S/C42H45ClN4O6/c1-27-33(5-3-8-38(27)51-16-4-13-46-14-11-32(48)12-15-46)34-6-2-7-36-35(34)9-10-39(36)53-41-19-40(52-26-29-17-28(20-44)21-45-22-29)30(18-37(41)43)23-47-24-31(25-47)42(49)50/h2-3,5-8,17-19,21-22,31-32,39,48H,4,9-16,23-26H2,1H3,(H,49,50)/t39-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482363 (US10919852, Compound TABLE 1.62 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H]2CCCC[C@H]2O)cc1Cl |r| Show InChI InChI=1S/C44H51ClN4O5/c1-29-34(7-5-12-41(29)52-20-6-17-49-18-15-33(50)16-19-49)35-8-4-9-37-36(35)13-14-42(37)54-44-23-43(53-28-31-21-30(24-46)25-47-26-31)32(22-38(44)45)27-48-39-10-2-3-11-40(39)51/h4-5,7-9,12,21-23,25-26,33,39-40,42,48,50-51H,2-3,6,10-11,13-20,27-28H2,1H3/t39-,40-,42+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482365 (US10919852, Compound TABLE 1.64 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CC(O)C2)cc1Cl |r| Show InChI InChI=1S/C41H45ClN4O5/c1-27-33(5-3-8-38(27)49-16-4-13-45-14-11-31(47)12-15-45)34-6-2-7-36-35(34)9-10-39(36)51-41-19-40(50-26-29-17-28(20-43)21-44-22-29)30(18-37(41)42)23-46-24-32(48)25-46/h2-3,5-8,17-19,21-22,31-32,39,47-48H,4,9-16,23-26H2,1H3/t39-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482366 (US10919852, Compound TABLE 1.65 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCc2cn(C)cn2)cc1Cl |r| Show InChI InChI=1S/C43H47ClN6O4/c1-29-35(6-4-9-40(29)52-17-5-14-50-15-12-34(51)13-16-50)36-7-3-8-38-37(36)10-11-41(38)54-43-20-42(53-27-31-18-30(21-45)22-46-23-31)32(19-39(43)44)24-47-25-33-26-49(2)28-48-33/h3-4,6-9,18-20,22-23,26,28,34,41,47,51H,5,10-17,24-25,27H2,1-2H3/t41-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482367 (US10919852, Compound TABLE 1.66 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H]2CCC[C@H]2O)cc1Cl |r| Show InChI InChI=1S/C43H49ClN4O5/c1-28-33(6-3-11-40(28)51-19-5-16-48-17-14-32(49)15-18-48)34-7-2-8-36-35(34)12-13-41(36)53-43-22-42(52-27-30-20-29(23-45)24-46-25-30)31(21-37(43)44)26-47-38-9-4-10-39(38)50/h2-3,6-8,11,20-22,24-25,32,38-39,41,47,49-50H,4-5,9-10,12-19,26-27H2,1H3/t38-,39-,41+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482368 (US10919852, Compound TABLE 1.67 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNC2(CCC2)C(O)=O)cc1Cl |r| Show InChI InChI=1S/C43H47ClN4O6/c1-28-33(6-3-9-38(28)52-19-5-16-48-17-12-32(49)13-18-48)34-7-2-8-36-35(34)10-11-39(36)54-41-22-40(53-27-30-20-29(23-45)24-46-25-30)31(21-37(41)44)26-47-43(42(50)51)14-4-15-43/h2-3,6-9,20-22,24-25,32,39,47,49H,4-5,10-19,26-27H2,1H3,(H,50,51)/t39-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482369 (US10919852, Compound TABLE 1.68 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H](CNC(N)=N)C(O)=O)cc1Cl |r| Show InChI InChI=1S/C42H48ClN7O6/c1-26-31(5-3-8-37(26)54-16-4-13-50-14-11-30(51)12-15-50)32-6-2-7-34-33(32)9-10-38(34)56-40-19-39(55-25-28-17-27(20-44)21-47-22-28)29(18-35(40)43)23-48-36(41(52)53)24-49-42(45)46/h2-3,5-8,17-19,21-22,30,36,38,48,51H,4,9-16,23-25H2,1H3,(H,52,53)(H4,45,46,49)/t36-,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482370 (US10919852, Compound TABLE 1.69 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CCC(C)(O)CC2)cc1Cl |r| Show InChI InChI=1S/C44H51ClN4O5/c1-30-35(6-4-9-40(30)52-21-5-16-48-17-12-34(50)13-18-48)36-7-3-8-38-37(36)10-11-41(38)54-43-24-42(53-29-32-22-31(25-46)26-47-27-32)33(23-39(43)45)28-49-19-14-44(2,51)15-20-49/h3-4,6-9,22-24,26-27,34,41,50-51H,5,10-21,28-29H2,1-2H3/t41-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482371 (US10919852, Compound TABLE 1.70 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC(F)(F)C3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C40H41ClF2N4O6/c1-24-29(6-4-9-34(24)51-13-5-12-47-22-40(42,43)23-47)30-7-3-8-32-31(30)10-11-35(32)53-37-16-36(52-21-27-14-26(17-44)18-45-19-27)28(15-33(37)41)20-46-38(25(2)48)39(49)50/h3-4,6-9,14-16,18-19,25,35,38,46,48H,5,10-13,20-23H2,1-2H3,(H,49,50)/t25-,35+,38+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482372 (US10919852, Compound TABLE 1.71 | US11708326, Comp...) Show SMILES COC(=O)C1(O)CCN(CCCOc2cccc(c2C)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN[C@@H]([C@@H](C)O)C(O)=O)cc2Cl)C1 |r| Show InChI InChI=1S/C43H47ClN4O9/c1-26-31(7-5-10-36(26)55-16-6-14-48-15-13-43(53,25-48)42(52)54-3)32-8-4-9-34-33(32)11-12-37(34)57-39-19-38(56-24-29-17-28(20-45)21-46-22-29)30(18-35(39)44)23-47-40(27(2)49)41(50)51/h4-5,7-10,17-19,21-22,27,37,40,47,49,53H,6,11-16,23-25H2,1-3H3,(H,50,51)/t27-,37+,40+,43?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482373 (US10919852, Compound TABLE 1.72 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CC(C)(O)C2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C42H46ClN5O5/c1-27-32(6-4-9-37(27)51-15-5-14-48-25-42(2,50)26-48)33-7-3-8-35-34(33)11-12-38(35)53-40-18-39(52-24-29-16-28(19-44)20-45-21-29)30(17-36(40)43)22-46-23-31-10-13-41(49)47-31/h3-4,6-9,16-18,20-21,31,38,46,50H,5,10-15,22-26H2,1-2H3,(H,47,49)/t31?,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482374 (US10919852, Compound TABLE 1.73 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2C3CCC2CC(O)C3)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C45H50ClN5O5/c1-28-36(5-3-8-41(28)54-16-4-15-51-33-10-11-34(51)20-35(52)19-33)37-6-2-7-39-38(37)12-13-42(39)56-44-21-43(55-27-30-17-29(22-47)23-48-24-30)31(18-40(44)46)25-49-26-32-9-14-45(53)50-32/h2-3,5-8,17-18,21,23-24,32-35,42,49,52H,4,9-16,19-20,25-27H2,1H3,(H,50,53)/t32?,33?,34?,35?,42-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482375 (US10919852, Compound TABLE 1.74 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CC(F)(F)C2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H]2CCCC[C@@H]2O)cc1Cl |r| Show InChI InChI=1S/C42H45ClF2N4O4/c1-27-31(7-5-12-38(27)51-16-6-15-49-25-42(44,45)26-49)32-8-4-9-34-33(32)13-14-39(34)53-41-19-40(52-24-29-17-28(20-46)21-47-22-29)30(18-35(41)43)23-48-36-10-2-3-11-37(36)50/h4-5,7-9,12,17-19,21-22,36-37,39,48,50H,2-3,6,10-11,13-16,23-26H2,1H3/t36-,37+,39+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482376 (US10919852, Compound TABLE 1.75 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(F)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C43H47ClFN5O4/c1-28-34(5-3-8-39(28)52-18-4-15-50-16-13-32(45)14-17-50)35-6-2-7-37-36(35)10-11-40(37)54-42-21-41(53-27-30-19-29(22-46)23-47-24-30)31(20-38(42)44)25-48-26-33-9-12-43(51)49-33/h2-3,5-8,19-21,23-24,32-33,40,48H,4,9-18,25-27H2,1H3,(H,49,51)/t33?,40-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482377 (US10919852, Compound TABLE 1.76 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CC(O)C2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C41H44ClN5O5/c1-26-32(5-3-8-37(26)50-14-4-13-47-23-31(48)24-47)33-6-2-7-35-34(33)10-11-38(35)52-40-17-39(51-25-28-15-27(18-43)19-44-20-28)29(16-36(40)42)21-45-22-30-9-12-41(49)46-30/h2-3,5-8,15-17,19-20,30-31,38,45,48H,4,9-14,21-25H2,1H3,(H,46,49)/t30?,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482378 (US10919852, Compound TABLE 1.77 | US11708326, Comp...) Show SMILES OC1CCN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNCC3CCC(=O)N3)cc2Cl)CC1 |r| Show InChI InChI=1S/C42H45Cl2N5O5/c43-36-19-29(24-47-25-30-8-11-41(51)48-30)39(53-26-28-18-27(21-45)22-46-23-28)20-40(36)54-37-10-9-33-32(4-1-5-34(33)37)35-6-2-7-38(42(35)44)52-17-3-14-49-15-12-31(50)13-16-49/h1-2,4-7,18-20,22-23,30-31,37,47,50H,3,8-17,24-26H2,(H,48,51)/t30?,37-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482379 (US10919852, Compound TABLE 1.78 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2Cl)cc1OCc1cncc(c1)C#N)C(N)=O |r| Show InChI InChI=1S/C41H45Cl2N5O6/c1-25(49)40(41(45)51)47-23-28-18-34(42)38(19-37(28)53-24-27-17-26(20-44)21-46-22-27)54-35-10-9-31-30(5-2-6-32(31)35)33-7-3-8-36(39(33)43)52-16-4-13-48-14-11-29(50)12-15-48/h2-3,5-8,17-19,21-22,25,29,35,40,47,49-50H,4,9-16,23-24H2,1H3,(H2,45,51)/t25-,35+,40+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482381 (US10919852, Compound TABLE 1.80 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@@H](Oc3cc(OCc4cncc(c4)C#N)c(CN[C@@H](CO)C(O)=O)cc3Cl)[C@H](F)Cc12 |r| Show InChI InChI=1S/C41H44ClFN4O7/c1-25-30(5-3-8-37(25)52-14-4-11-47-12-9-29(49)10-13-47)31-6-2-7-32-33(31)17-35(43)40(32)54-39-18-38(53-24-27-15-26(19-44)20-45-21-27)28(16-34(39)42)22-46-36(23-48)41(50)51/h2-3,5-8,15-16,18,20-21,29,35-36,40,46,48-49H,4,9-14,17,22-24H2,1H3,(H,50,51)/t35-,36+,40-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482382 (US10919852, Compound TABLE 1.81 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2[C@@H](F)Cc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C42H46ClFN4O7/c1-25-31(6-4-9-37(25)53-15-5-12-48-13-10-30(50)11-14-48)32-7-3-8-33-34(32)18-36(44)41(33)55-39-19-38(54-24-28-16-27(20-45)21-46-22-28)29(17-35(39)43)23-47-40(26(2)49)42(51)52/h3-4,6-9,16-17,19,21-22,26,30,36,40-41,47,49-50H,5,10-15,18,23-24H2,1-2H3,(H,51,52)/t26-,36+,40+,41-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482383 (US10919852, Compound TABLE 1.82 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@@H](Oc3cc(OCc4cncc(c4)C#N)c(CN[C@@](C)(CO)C(O)=O)cc3Cl)[C@@H](F)Cc12 |r| Show InChI InChI=1S/C42H46ClFN4O7/c1-26-31(6-4-9-37(26)53-15-5-12-48-13-10-30(50)11-14-48)32-7-3-8-33-34(32)18-36(44)40(33)55-39-19-38(54-24-28-16-27(20-45)21-46-22-28)29(17-35(39)43)23-47-42(2,25-49)41(51)52/h3-4,6-9,16-17,19,21-22,30,36,40,47,49-50H,5,10-15,18,23-25H2,1-2H3,(H,51,52)/t36-,40+,42-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482384 (US10919852, Compound TABLE 1.83 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@@H](Oc3cc(OCc4cncc(c4)C#N)c(CN[C@@H]4CCCC[C@@H]4O)cc3Cl)[C@@H](F)Cc12 |r| Show InChI InChI=1S/C44H50ClFN4O5/c1-28-33(7-5-12-41(28)53-18-6-15-50-16-13-32(51)14-17-50)34-8-4-9-35-36(34)21-38(46)44(35)55-43-22-42(54-27-30-19-29(23-47)24-48-25-30)31(20-37(43)45)26-49-39-10-2-3-11-40(39)52/h4-5,7-9,12,19-20,22,24-25,32,38-40,44,49,51-52H,2-3,6,10-11,13-18,21,26-27H2,1H3/t38-,39+,40-,44+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482385 (US10919852, Compound TABLE 1.84 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(C)(O)CC3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C43H49ClN4O7/c1-27-32(7-5-10-37(27)53-18-6-15-48-16-13-43(3,52)14-17-48)33-8-4-9-35-34(33)11-12-38(35)55-40-21-39(54-26-30-19-29(22-45)23-46-24-30)31(20-36(40)44)25-47-41(28(2)49)42(50)51/h4-5,7-10,19-21,23-24,28,38,41,47,49,52H,6,11-18,25-26H2,1-3H3,(H,50,51)/t28-,38+,41+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482386 (US10919852, Compound TABLE 1.85 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CC[C@H](F)C2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H]2CCCC[C@@H]2O)cc1Cl |r| Show InChI InChI=1S/C43H48ClFN4O4/c1-28-33(7-5-12-40(28)51-18-6-16-49-17-15-32(45)26-49)34-8-4-9-36-35(34)13-14-41(36)53-43-21-42(52-27-30-19-29(22-46)23-47-24-30)31(20-37(43)44)25-48-38-10-2-3-11-39(38)50/h4-5,7-9,12,19-21,23-24,32,38-39,41,48,50H,2-3,6,10-11,13-18,25-27H2,1H3/t32-,38+,39-,41-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482387 (US10919852, Compound TABLE 1.86 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CC[C@@H](F)C2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H]2CCCC[C@@H]2O)cc1Cl |r| Show InChI InChI=1S/C43H48ClFN4O4/c1-28-33(7-5-12-40(28)51-18-6-16-49-17-15-32(45)26-49)34-8-4-9-36-35(34)13-14-41(36)53-43-21-42(52-27-30-19-29(22-46)23-47-24-30)31(20-37(43)44)25-48-38-10-2-3-11-39(38)50/h4-5,7-9,12,19-21,23-24,32,38-39,41,48,50H,2-3,6,10-11,13-18,25-27H2,1H3/t32-,38-,39+,41+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482305 (US10919852, Compound TABLE 1.4 | US10919852, Compo...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C42H47ClN4O7/c1-26-32(6-4-9-37(26)52-17-5-14-47-15-12-31(49)13-16-47)33-7-3-8-35-34(33)10-11-38(35)54-40-20-39(53-25-29-18-28(21-44)22-45-23-29)30(19-36(40)43)24-46-41(27(2)48)42(50)51/h3-4,6-9,18-20,22-23,27,31,38,41,46,48-49H,5,10-17,24-25H2,1-2H3,(H,50,51)/t27-,38+,41+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482389 (US10919852, Compound TABLE 1.88 | US11708326, Comp...) Show SMILES CC(CO)(CO)NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCNC(=O)C3)c2Cl)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C40H43Cl2N5O6/c1-40(24-48,25-49)46-21-28-16-33(41)37(17-36(28)52-23-27-15-26(18-43)19-44-20-27)53-34-10-9-30-29(5-2-6-31(30)34)32-7-3-8-35(39(32)42)51-14-4-12-47-13-11-45-38(50)22-47/h2-3,5-8,15-17,19-20,34,46,48-49H,4,9-14,21-25H2,1H3,(H,45,50)/t34-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482390 (US10919852, Compound TABLE 1.89 | US11708326, Comp...) Show SMILES OC(=O)C1(CCC1)NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCNC(=O)C3)c2Cl)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C41H41Cl2N5O6/c42-33-18-28(23-47-41(40(50)51)11-3-12-41)36(53-25-27-17-26(20-44)21-45-22-27)19-37(33)54-34-10-9-30-29(5-1-6-31(30)34)32-7-2-8-35(39(32)43)52-16-4-14-48-15-13-46-38(49)24-48/h1-2,5-8,17-19,21-22,34,47H,3-4,9-16,23-25H2,(H,46,49)(H,50,51)/t34-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482391 (US10919852, Compound TABLE 1.90 | US11708326, Comp...) Show SMILES O[C@H]1CCCC[C@H]1NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC4(CC(F)C4)C3)c2Cl)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C44H47Cl2FN4O4/c45-36-17-30(24-50-37-9-1-2-10-38(37)52)41(54-25-29-16-28(21-48)22-49-23-29)18-42(36)55-39-13-12-33-32(6-3-7-34(33)39)35-8-4-11-40(43(35)46)53-15-5-14-51-26-44(27-51)19-31(47)20-44/h3-4,6-8,11,16-18,22-23,31,37-39,50,52H,1-2,5,9-10,12-15,19-20,24-27H2/t37-,38+,39+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482392 (US10919852, Compound TABLE 1.91 | US11708326, Comp...) Show SMILES O[C@H]1CCCC[C@H]1NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC4(C3)CC(F)(F)C4)c2Cl)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C44H46Cl2F2N4O4/c45-35-17-30(22-51-36-9-1-2-10-37(36)53)40(55-23-29-16-28(19-49)20-50-21-29)18-41(35)56-38-13-12-32-31(6-3-7-33(32)38)34-8-4-11-39(42(34)46)54-15-5-14-52-26-43(27-52)24-44(47,48)25-43/h3-4,6-8,11,16-18,20-21,36-38,51,53H,1-2,5,9-10,12-15,22-27H2/t36-,37+,38+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482393 (US10919852, Compound TABLE 1.92 | US11708326, Comp...) Show SMILES O[C@H]1CCCC[C@H]1NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC(F)C3)c2Cl)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C41H43Cl2FN4O4/c42-34-17-28(22-47-35-9-1-2-10-36(35)49)39(51-25-27-16-26(19-45)20-46-21-27)18-40(34)52-37-13-12-31-30(6-3-7-32(31)37)33-8-4-11-38(41(33)43)50-15-5-14-48-23-29(44)24-48/h3-4,6-8,11,16-18,20-21,29,35-37,47,49H,1-2,5,9-10,12-15,22-25H2/t35-,36+,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482394 (US10919852, Compound TABLE 1.93 | US11708326, Comp...) Show SMILES Cc1c(OCCCNCC(C)(C)O)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C42H48ClN5O5/c1-27-32(7-5-10-37(27)51-16-6-15-45-26-42(2,3)50)33-8-4-9-35-34(33)12-13-38(35)53-40-19-39(52-25-29-17-28(20-44)21-46-22-29)30(18-36(40)43)23-47-24-31-11-14-41(49)48-31/h4-5,7-10,17-19,21-22,31,38,45,47,50H,6,11-16,23-26H2,1-3H3,(H,48,49)/t31?,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482397 (US10919852, Compound TABLE 1.96 | US11708326, Comp...) Show SMILES CC(C)(O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(F)CC3)c2Cl)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C42H45Cl2FN4O6/c1-42(2,52)40(41(50)51)48-24-28-19-34(43)38(20-37(28)54-25-27-18-26(21-46)22-47-23-27)55-35-11-10-31-30(6-3-7-32(31)35)33-8-4-9-36(39(33)44)53-17-5-14-49-15-12-29(45)13-16-49/h3-4,6-9,18-20,22-23,29,35,40,48,52H,5,10-17,24-25H2,1-2H3,(H,50,51)/t35-,40+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482462 (US10919852, Compound TABLE 1.161 | US11708326, Com...) Show SMILES F[C@@H]1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(OCCCN4CCC(F)CC4)c3Cl)cc2OCc2cncc(c2)C#N)C1 |r| Show InChI InChI=1S/C41H42Cl2F2N4O3/c42-36-19-29(24-49-16-12-31(45)25-49)39(51-26-28-18-27(21-46)22-47-23-28)20-40(36)52-37-9-8-33-32(4-1-5-34(33)37)35-6-2-7-38(41(35)43)50-17-3-13-48-14-10-30(44)11-15-48/h1-2,4-7,18-20,22-23,30-31,37H,3,8-17,24-26H2/t31-,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482463 (US10919852, Compound TABLE 1.162 | US11708326, Com...) Show SMILES CC1(O)CN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(OCCCN4CCC(F)CC4)c3Cl)cc2OCc2cncc(c2)C#N)C1 |r| Show InChI InChI=1S/C41H43Cl2FN4O4/c1-41(49)25-48(26-41)23-29-18-35(42)39(19-38(29)51-24-28-17-27(20-45)21-46-22-28)52-36-10-9-32-31(5-2-6-33(32)36)34-7-3-8-37(40(34)43)50-16-4-13-47-14-11-30(44)12-15-47/h2-3,5-8,17-19,21-22,30,36,49H,4,9-16,23-26H2,1H3/t36-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482464 (US10919852, Compound TABLE 1.163 | US11708326, Com...) Show SMILES CC1(O)CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(OCCCN4CCC(F)CC4)c3Cl)cc2OCc2cncc(c2)C#N)CC1 |r| Show InChI InChI=1S/C43H47Cl2FN4O4/c1-43(51)13-18-50(19-14-43)27-31-22-37(44)41(23-40(31)53-28-30-21-29(24-47)25-48-26-30)54-38-10-9-34-33(5-2-6-35(34)38)36-7-3-8-39(42(36)45)52-20-4-15-49-16-11-32(46)12-17-49/h2-3,5-8,21-23,25-26,32,38,51H,4,9-20,27-28H2,1H3/t38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482465 (US10919852, Compound TABLE 1.164 | US11708326, Com...) Show SMILES OC1CC2(C1)CN(CCCOc1cccc(c1Cl)-c1cccc3[C@H](CCc13)Oc1cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc1Cl)C2 |r| Show InChI InChI=1S/C43H45Cl2N5O5/c44-36-15-29(22-48-23-30-8-11-41(52)49-30)39(54-24-28-14-27(19-46)20-47-21-28)16-40(36)55-37-10-9-33-32(4-1-5-34(33)37)35-6-2-7-38(42(35)45)53-13-3-12-50-25-43(26-50)17-31(51)18-43/h1-2,4-7,14-16,20-21,30-31,37,48,51H,3,8-13,17-18,22-26H2,(H,49,52)/t30-,37-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 416 total )  |  Next  |  Last  >>

Jump to: