Compile Data Set for Download or QSAR

Found 90 hits Enz. Inhib. hit(s) with all data for entry = 9807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490058 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2cccnc2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C25H27FN4O4S/c1-25(2,3)30-35(33,34)21-12-10-20(11-13-21)28-24(32)22(15-17-5-4-14-27-16-17)29-23(31)18-6-8-19(26)9-7-18/h4-14,16,22,30H,15H2,1-3H3,(H,28,32)(H,29,31)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490029 ((S)-N-(1-((4-(tert- butyl)sulfamoyl)phenyl)amino)-...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C26H28FN3O4S/c1-26(2,3)30-35(33,34)22-15-13-21(14-16-22)28-25(32)23(17-18-7-5-4-6-8-18)29-24(31)19-9-11-20(27)12-10-19/h4-16,23,30H,17H2,1-3H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490051 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2cccs2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C24H26FN3O4S2/c1-24(2,3)28-34(31,32)20-12-10-18(11-13-20)26-23(30)21(15-19-5-4-14-33-19)27-22(29)16-6-8-17(25)9-7-16/h4-14,21,28H,15H2,1-3H3,(H,26,30)(H,27,29)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490068 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccncc2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C25H27FN4O4S/c1-25(2,3)30-35(33,34)21-10-8-20(9-11-21)28-24(32)22(16-17-12-14-27-15-13-17)29-23(31)18-4-6-19(26)7-5-18/h4-15,22,30H,16H2,1-3H3,(H,28,32)(H,29,31)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490050 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES COc1ccc(C[C@H](NC(=O)c2ccc(F)cc2)C(=O)Nc2ccc(cc2)S(=O)(=O)NC(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H30FN3O5S/c1-27(2,3)31-37(34,35)23-15-11-21(12-16-23)29-26(33)24(17-18-5-13-22(36-4)14-6-18)30-25(32)19-7-9-20(28)10-8-19/h5-16,24,31H,17H2,1-4H3,(H,29,33)(H,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490037 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C26H34FN3O4S/c1-26(2,3)30-35(33,34)22-15-13-21(14-16-22)28-25(32)23(17-18-7-5-4-6-8-18)29-24(31)19-9-11-20(27)12-10-19/h9-16,18,23,30H,4-8,17H2,1-3H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490055 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C26H27F2N3O4S/c1-26(2,3)31-36(34,35)22-14-12-21(13-15-22)29-25(33)23(16-17-4-8-19(27)9-5-17)30-24(32)18-6-10-20(28)11-7-18/h4-15,23,31H,16H2,1-3H3,(H,29,33)(H,30,32)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490045 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2cccs2)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-24(2,3)27-33(30,31)20-13-11-18(12-14-20)25-23(29)21(16-19-10-7-15-32-19)26-22(28)17-8-5-4-6-9-17/h7,10-15,17,21,27H,4-6,8-9,16H2,1-3H3,(H,25,29)(H,26,28)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490028 ((R)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@@H](Cc2ccccc2)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C26H35N3O4S/c1-26(2,3)29-34(32,33)22-16-14-21(15-17-22)27-25(31)23(18-19-10-6-4-7-11-19)28-24(30)20-12-8-5-9-13-20/h4,6-7,10-11,14-17,20,23,29H,5,8-9,12-13,18H2,1-3H3,(H,27,31)(H,28,30)/t23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490042 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(F)c(F)c2)cc1 |r| Show InChI InChI=1S/C26H33F2N3O4S/c1-26(2,3)31-36(34,35)20-12-10-19(11-13-20)29-25(33)23(15-17-7-5-4-6-8-17)30-24(32)18-9-14-21(27)22(28)16-18/h9-14,16-17,23,31H,4-8,15H2,1-3H3,(H,29,33)(H,30,32)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490073 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2cccc(c2)C#N)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C27H34N4O4S/c1-27(2,3)31-36(34,35)23-14-12-22(13-15-23)29-26(33)24(17-19-8-7-9-20(16-19)18-28)30-25(32)21-10-5-4-6-11-21/h7-9,12-16,21,24,31H,4-6,10-11,17H2,1-3H3,(H,29,33)(H,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490059 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccn2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C25H27FN4O4S/c1-25(2,3)30-35(33,34)21-13-11-19(12-14-21)28-24(32)22(16-20-6-4-5-15-27-20)29-23(31)17-7-9-18(26)10-8-17/h4-15,22,30H,16H2,1-3H3,(H,28,32)(H,29,31)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489719 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccc(F)cc3)cccc12 |r| Show InChI InChI=1S/C30H30FN3O4S/c1-30(2,3)34-39(37,38)27-14-8-11-23-24(27)12-7-13-25(23)32-29(36)26(19-20-9-5-4-6-10-20)33-28(35)21-15-17-22(31)18-16-21/h4-18,26,34H,19H2,1-3H3,(H,32,36)(H,33,35)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490041 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2cccc(F)c2)cc1 |r| Show InChI InChI=1S/C26H34FN3O4S/c1-26(2,3)30-35(33,34)22-14-12-21(13-15-22)28-25(32)23(16-18-8-5-4-6-9-18)29-24(31)19-10-7-11-20(27)17-19/h7,10-15,17-18,23,30H,4-6,8-9,16H2,1-3H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490026 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C26H35N3O4S/c1-26(2,3)29-34(32,33)22-16-14-21(15-17-22)27-25(31)23(18-19-10-6-4-7-11-19)28-24(30)20-12-8-5-9-13-20/h4,6-7,10-11,14-17,20,23,29H,5,8-9,12-13,18H2,1-3H3,(H,27,31)(H,28,30)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490072 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCOCC2)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C25H39N3O5S/c1-25(2,3)28-34(31,32)21-11-9-20(10-12-21)26-24(30)22(17-18-13-15-33-16-14-18)27-23(29)19-7-5-4-6-8-19/h9-12,18-19,22,28H,4-8,13-17H2,1-3H3,(H,26,30)(H,27,29)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490027 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)C2CCCC2)cc1 |r| Show InChI InChI=1S/C25H33N3O4S/c1-25(2,3)28-33(31,32)21-15-13-20(14-16-21)26-24(30)22(17-18-9-5-4-6-10-18)27-23(29)19-11-7-8-12-19/h4-6,9-10,13-16,19,22,28H,7-8,11-12,17H2,1-3H3,(H,26,30)(H,27,29)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490036 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C26H41N3O4S/c1-26(2,3)29-34(32,33)22-16-14-21(15-17-22)27-25(31)23(18-19-10-6-4-7-11-19)28-24(30)20-12-8-5-9-13-20/h14-17,19-20,23,29H,4-13,18H2,1-3H3,(H,27,31)(H,28,30)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490016 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES COc1ccc(C[C@H](NC(=O)c2ccccc2)C(=O)Nc2cccc3c(cccc23)S(=O)(=O)NC(C)(C)C)cc1 |r| Show InChI InChI=1S/C31H33N3O5S/c1-31(2,3)34-40(37,38)28-15-9-12-24-25(28)13-8-14-26(24)32-30(36)27(20-21-16-18-23(39-4)19-17-21)33-29(35)22-10-6-5-7-11-22/h5-19,27,34H,20H2,1-4H3,(H,32,36)(H,33,35)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489727 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCC(F)(F)CC3)cccc12 |r| Show InChI InChI=1S/C30H35F2N3O4S/c1-29(2,3)35-40(38,39)26-14-8-11-22-23(26)12-7-13-24(22)33-28(37)25(19-20-9-5-4-6-10-20)34-27(36)21-15-17-30(31,32)18-16-21/h4-14,21,25,35H,15-19H2,1-3H3,(H,33,37)(H,34,36)/t25-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490039 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)C2CCCC2)cc1 |r| Show InChI InChI=1S/C25H39N3O4S/c1-25(2,3)28-33(31,32)21-15-13-20(14-16-21)26-24(30)22(17-18-9-5-4-6-10-18)27-23(29)19-11-7-8-12-19/h13-16,18-19,22,28H,4-12,17H2,1-3H3,(H,26,30)(H,27,29)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490044 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccccn2)cc1 |r| Show InChI InChI=1S/C25H34N4O4S/c1-25(2,3)29-34(32,33)20-14-12-19(13-15-20)27-24(31)22(17-18-9-5-4-6-10-18)28-23(30)21-11-7-8-16-26-21/h7-8,11-16,18,22,29H,4-6,9-10,17H2,1-3H3,(H,27,31)(H,28,30)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489704 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCCC3)cccc12 |r| Show InChI InChI=1S/C30H37N3O4S/c1-30(2,3)33-38(36,37)27-19-11-16-23-24(27)17-10-18-25(23)31-29(35)26(20-21-12-6-4-7-13-21)32-28(34)22-14-8-5-9-15-22/h4,6-7,10-13,16-19,22,26,33H,5,8-9,14-15,20H2,1-3H3,(H,31,35)(H,32,34)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490046 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)c2ccccc2)cc1 |r| Show InChI InChI=1S/C26H28FN3O4S/c1-26(2,3)30-35(33,34)22-15-13-21(14-16-22)28-25(32)23(17-18-9-11-20(27)12-10-18)29-24(31)19-7-5-4-6-8-19/h4-16,23,30H,17H2,1-3H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490034 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2cccnn2)cc1 |r| Show InChI InChI=1S/C24H27N5O4S/c1-24(2,3)29-34(32,33)19-13-11-18(12-14-19)26-23(31)21(16-17-8-5-4-6-9-17)27-22(30)20-10-7-15-25-28-20/h4-15,21,29H,16H2,1-3H3,(H,26,31)(H,27,30)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490015 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccc(F)cc3)NC(=O)c3ccccc3)cccc12 |r| Show InChI InChI=1S/C30H30FN3O4S/c1-30(2,3)34-39(37,38)27-14-8-11-23-24(27)12-7-13-25(23)32-29(36)26(19-20-15-17-22(31)18-16-20)33-28(35)21-9-5-4-6-10-21/h4-18,26,34H,19H2,1-3H3,(H,32,36)(H,33,35)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490056 ((S)-N-(3-([1,1'-biphenyl]-4-yl)-1- ((4-(N-(tert- b...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C32H32FN3O4S/c1-32(2,3)36-41(39,40)28-19-17-27(18-20-28)34-31(38)29(35-30(37)25-13-15-26(33)16-14-25)21-22-9-11-24(12-10-22)23-7-5-4-6-8-23/h4-20,29,36H,21H2,1-3H3,(H,34,38)(H,35,37)/t29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489745 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccccn3)cccc12 |r| Show InChI InChI=1S/C29H30N4O4S/c1-29(2,3)33-38(36,37)26-17-10-13-21-22(26)14-9-16-23(21)31-28(35)25(19-20-11-5-4-6-12-20)32-27(34)24-15-7-8-18-30-24/h4-18,25,33H,19H2,1-3H3,(H,31,35)(H,32,34)/t25-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490052 ((S)-N-(1-((4-(N- isopropylsulfamoyl)phenyl)amino)-...) Show SMILES CC(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C25H33N3O4S/c1-18(2)28-33(31,32)22-15-13-21(14-16-22)26-25(30)23(17-19-9-5-3-6-10-19)27-24(29)20-11-7-4-8-12-20/h3,5-6,9-10,13-16,18,20,23,28H,4,7-8,11-12,17H2,1-2H3,(H,26,30)(H,27,29)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489738 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)c3nccs3)cccc12 |r| Show InChI InChI=1S/C27H28N4O4S2/c1-27(2,3)31-37(34,35)23-14-8-11-19-20(23)12-7-13-21(19)29-24(32)22(17-18-9-5-4-6-10-18)30-25(33)26-28-15-16-36-26/h4-16,22,31H,17H2,1-3H3,(H,29,32)(H,30,33)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490060 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](CC3CCCCC3)NC(=O)C3CCCCC3)cccc12 |r| Show InChI InChI=1S/C30H43N3O4S/c1-30(2,3)33-38(36,37)27-19-11-16-23-24(27)17-10-18-25(23)31-29(35)26(20-21-12-6-4-7-13-21)32-28(34)22-14-8-5-9-15-22/h10-11,16-19,21-22,26,33H,4-9,12-15,20H2,1-3H3,(H,31,35)(H,32,34)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490064 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES COc1ccc(C[C@H](NC(=O)c2ccccn2)C(=O)Nc2ccc(cc2)S(=O)(=O)NC(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H30N4O5S/c1-26(2,3)30-36(33,34)21-14-10-19(11-15-21)28-25(32)23(17-18-8-12-20(35-4)13-9-18)29-24(31)22-7-5-6-16-27-22/h5-16,23,30H,17H2,1-4H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490062 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2cccs2)NC(=O)c2ccccn2)cc1 |r| Show InChI InChI=1S/C23H26N4O4S2/c1-23(2,3)27-33(30,31)18-11-9-16(10-12-18)25-22(29)20(15-17-7-6-14-32-17)26-21(28)19-8-4-5-13-24-19/h4-14,20,27H,15H2,1-3H3,(H,25,29)(H,26,28)/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490070 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES COc1ccc(C[C@H](NC(=O)c2cccnc2)C(=O)Nc2ccc(cc2)S(=O)(=O)NC(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H30N4O5S/c1-26(2,3)30-36(33,34)22-13-9-20(10-14-22)28-25(32)23(16-18-7-11-21(35-4)12-8-18)29-24(31)19-6-5-15-27-17-19/h5-15,17,23,30H,16H2,1-4H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490035 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccccc2)cc1 |r| Show InChI InChI=1S/C26H35N3O4S/c1-26(2,3)29-34(32,33)22-16-14-21(15-17-22)27-25(31)23(18-19-10-6-4-7-11-19)28-24(30)20-12-8-5-9-13-20/h5,8-9,12-17,19,23,29H,4,6-7,10-11,18H2,1-3H3,(H,27,31)(H,28,30)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490021 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3cccs3)NC(=O)c3ccccc3)cccc12 |r| Show InChI InChI=1S/C28H29N3O4S2/c1-28(2,3)31-37(34,35)25-16-8-13-21-22(25)14-7-15-23(21)29-27(33)24(18-20-12-9-17-36-20)30-26(32)19-10-5-4-6-11-19/h4-17,24,31H,18H2,1-3H3,(H,29,33)(H,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489702 ((R)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@@H](Cc3ccccc3)NC(=O)c3ccccc3)cccc12 |r| Show InChI InChI=1S/C30H31N3O4S/c1-30(2,3)33-38(36,37)27-19-11-16-23-24(27)17-10-18-25(23)31-29(35)26(20-21-12-6-4-7-13-21)32-28(34)22-14-8-5-9-15-22/h4-19,26,33H,20H2,1-3H3,(H,31,35)(H,32,34)/t26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490032 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccccn2)cc1 |r| Show InChI InChI=1S/C25H28N4O4S/c1-25(2,3)29-34(32,33)20-14-12-19(13-15-20)27-24(31)22(17-18-9-5-4-6-10-18)28-23(30)21-11-7-8-16-26-21/h4-16,22,29H,17H2,1-3H3,(H,27,31)(H,28,30)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489739 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccc(cc3)C#N)cccc12 |r| Show InChI InChI=1S/C31H30N4O4S/c1-31(2,3)35-40(38,39)28-14-8-11-24-25(28)12-7-13-26(24)33-30(37)27(19-21-9-5-4-6-10-21)34-29(36)23-17-15-22(20-32)16-18-23/h4-18,27,35H,19H2,1-3H3,(H,33,37)(H,34,36)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	269	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490020 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccc(cc3)C#N)NC(=O)c3ccccc3)cccc12 |r| Show InChI InChI=1S/C31H30N4O4S/c1-31(2,3)35-40(38,39)28-14-8-11-24-25(28)12-7-13-26(24)33-30(37)27(19-21-15-17-22(20-32)18-16-21)34-29(36)23-9-5-4-6-10-23/h4-18,27,35H,19H2,1-3H3,(H,33,37)(H,34,36)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	273	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489703 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccccc3)cccc12 |r| Show InChI InChI=1S/C30H31N3O4S/c1-30(2,3)33-38(36,37)27-19-11-16-23-24(27)17-10-18-25(23)31-29(35)26(20-21-12-6-4-7-13-21)32-28(34)22-14-8-5-9-15-22/h4-19,26,33H,20H2,1-3H3,(H,31,35)(H,32,34)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	273	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490057 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)-3- fluorop...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)C2CCCCC2)cc1F |r| Show InChI InChI=1S/C26H34FN3O4S/c1-26(2,3)30-35(33,34)23-15-14-20(17-21(23)27)28-25(32)22(16-18-10-6-4-7-11-18)29-24(31)19-12-8-5-9-13-19/h4,6-7,10-11,14-15,17,19,22,30H,5,8-9,12-13,16H2,1-3H3,(H,28,32)(H,29,31)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489721 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCC3)cccc12 |r| Show InChI InChI=1S/C29H35N3O4S/c1-29(2,3)32-37(35,36)26-18-10-15-22-23(26)16-9-17-24(22)30-28(34)25(19-20-11-5-4-6-12-20)31-27(33)21-13-7-8-14-21/h4-6,9-12,15-18,21,25,32H,7-8,13-14,19H2,1-3H3,(H,30,34)(H,31,33)/t25-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	366	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490024 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccc(Cl)cc3)NC(=O)c3ccccc3)cccc12 |r| Show InChI InChI=1S/C30H30ClN3O4S/c1-30(2,3)34-39(37,38)27-14-8-11-23-24(27)12-7-13-25(23)32-29(36)26(19-20-15-17-22(31)18-16-20)33-28(35)21-9-5-4-6-10-21/h4-18,26,34H,19H2,1-3H3,(H,32,36)(H,33,35)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	446	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490040 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccccc2F)cc1 |r| Show InChI InChI=1S/C26H34FN3O4S/c1-26(2,3)30-35(33,34)20-15-13-19(14-16-20)28-25(32)23(17-18-9-5-4-6-10-18)29-24(31)21-11-7-8-12-22(21)27/h7-8,11-16,18,23,30H,4-6,9-10,17H2,1-3H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	461	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490012 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)c3ccccc3)cccc12 |r| Show InChI InChI=1S/C30H31N3O5S/c1-30(2,3)33-39(37,38)27-14-8-11-23-24(27)12-7-13-25(23)31-29(36)26(19-20-15-17-22(34)18-16-20)32-28(35)21-9-5-4-6-10-21/h4-18,26,33-34H,19H2,1-3H3,(H,31,36)(H,32,35)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490013 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](CC3CCCCC3)NC(=O)c3ccccc3)cccc12 |r| Show InChI InChI=1S/C30H37N3O4S/c1-30(2,3)33-38(36,37)27-19-11-16-23-24(27)17-10-18-25(23)31-29(35)26(20-21-12-6-4-7-13-21)32-28(34)22-14-8-5-9-15-22/h5,8-11,14-19,21,26,33H,4,6-7,12-13,20H2,1-3H3,(H,31,35)(H,32,34)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	666	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490047 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CC2)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C23H35N3O4S/c1-23(2,3)26-31(29,30)19-13-11-18(12-14-19)24-22(28)20(15-16-9-10-16)25-21(27)17-7-5-4-6-8-17/h11-14,16-17,20,26H,4-10,15H2,1-3H3,(H,24,28)(H,25,27)/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489709 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccc(Cl)cc3)cccc12 |r| Show InChI InChI=1S/C30H30ClN3O4S/c1-30(2,3)34-39(37,38)27-14-8-11-23-24(27)12-7-13-25(23)32-29(36)26(19-20-9-5-4-6-10-20)33-28(35)21-15-17-22(31)18-16-21/h4-18,26,34H,19H2,1-3H3,(H,32,36)(H,33,35)/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	833	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490063 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES COc1ccc(nc1)C(=O)N[C@@H](Cc1cccs1)C(=O)Nc1ccc(cc1)S(=O)(=O)NC(C)(C)C |r| Show InChI InChI=1S/C24H28N4O5S2/c1-24(2,3)28-35(31,32)19-10-7-16(8-11-19)26-23(30)21(14-18-6-5-13-34-18)27-22(29)20-12-9-17(33-4)15-25-20/h5-13,15,21,28H,14H2,1-4H3,(H,26,30)(H,27,29)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair

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