Compile Data Set for Download or QSAR

Found 68 hits Enz. Inhib. hit(s) with all data for entry = 9913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498860 ((R)—N-(3-(3-Chlorophenyl)isoxazol-5-yl)-2-(1-...) Show SMILES Clc1cccc(c1)-c1cc(NC(=O)C[C@H]2CCN(C2)C#N)on1 |r| Show InChI InChI=1S/C16H15ClN4O2/c17-13-3-1-2-12(7-13)14-8-16(23-20-14)19-15(22)6-11-4-5-21(9-11)10-18/h1-3,7-8,11H,4-6,9H2,(H,19,22)/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498879 (US11014912, Example 55) Show SMILES O=C(C[C@H]1CCN(C1)C#N)Nc1cc(on1)-c1cccc(c1)C#N Show InChI InChI=1S/C17H15N5O2/c18-9-12-2-1-3-14(6-12)15-8-16(21-24-15)20-17(23)7-13-4-5-22(10-13)11-19/h1-3,6,8,13H,4-5,7,10H2,(H,20,21,23)/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498878 (US11014912, Example 54) Show SMILES FC(F)(F)Oc1cccc(c1)-c1cc(NC(=O)C[C@H]2CCN(C2)C#N)on1 Show InChI InChI=1S/C17H15F3N4O3/c18-17(19,20)26-13-3-1-2-12(7-13)14-8-16(27-23-14)22-15(25)6-11-4-5-24(9-11)10-21/h1-3,7-8,11H,4-6,9H2,(H,22,25)/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498875 (US11014912, Example 51) Show SMILES O=C(C[C@H]1CCN(C1)C#N)Nc1cc(no1)-c1cccc(c1)C#N Show InChI InChI=1S/C17H15N5O2/c18-9-12-2-1-3-14(6-12)15-8-17(24-21-15)20-16(23)7-13-4-5-22(10-13)11-19/h1-3,6,8,13H,4-5,7,10H2,(H,20,23)/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498874 (US11014912, Example 50) Show SMILES C[C@@H]([C@@H]1CCN(C1)C#N)C(=O)Nc1cc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C17H17ClN4O2/c1-11(13-5-6-22(9-13)10-19)17(23)20-16-8-15(21-24-16)12-3-2-4-14(18)7-12/h2-4,7-8,11,13H,5-6,9H2,1H3,(H,20,23)/t11-,13+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498866 (US11014912, Example 42) Show SMILES Clc1cccc(c1)-c1cc(NC(=O)C[C@@H]2CCN(C2)C#N)on1 Show InChI InChI=1S/C16H15ClN4O2/c17-13-3-1-2-12(7-13)14-8-16(23-20-14)19-15(22)6-11-4-5-21(9-11)10-18/h1-3,7-8,11H,4-6,9H2,(H,19,22)/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498867 (US11014912, Example 43) Show SMILES COc1cccc(c1)-c1cc(NC(=O)C[C@H]2CCN(C2)C#N)on1 Show InChI InChI=1S/C17H18N4O3/c1-23-14-4-2-3-13(8-14)15-9-17(24-20-15)19-16(22)7-12-5-6-21(10-12)11-18/h2-4,8-9,12H,5-7,10H2,1H3,(H,19,22)/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498883 (US11014912, Example 59) Show SMILES Cc1cc(ccc1C#N)C1CN(C1)C(=O)C[C@@H]1CCN(C1)C#N Show InChI InChI=1S/C18H20N4O/c1-13-6-15(2-3-16(13)8-19)17-10-22(11-17)18(23)7-14-4-5-21(9-14)12-20/h2-3,6,14,17H,4-5,7,9-11H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498889 (US11014912, Example 67) Show SMILES COc1ccc(cc1-c1cnn(C)c1)C1CN(C1)C(=O)C[C@@H]1CCN(C1)C#N Show InChI InChI=1S/C21H25N5O2/c1-24-11-17(9-23-24)19-8-16(3-4-20(19)28-2)18-12-26(13-18)21(27)7-15-5-6-25(10-15)14-22/h3-4,8-9,11,15,18H,5-7,10,12-13H2,1-2H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498846 (2-(1-Cyanopyrrolidin-3- ylidene)-N-(4- phenoxyphen...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)C=C1CCN(C1)C#N |w:16.17| Show InChI InChI=1S/C19H17N3O2/c20-14-22-11-10-15(13-22)12-19(23)21-16-6-8-18(9-7-16)24-17-4-2-1-3-5-17/h1-9,12H,10-11,13H2,(H,21,23)/b15-12-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498864 ((S)-3-(2-(3-(4-Methoxy-3-(1-methyl-1H-pyrazol-5-yl...) Show SMILES COc1ccc(cc1-c1ccnn1C)C1CN(C1)C(=O)C[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C21H25N5O2/c1-24-19(5-7-23-24)18-10-16(3-4-20(18)28-2)17-12-26(13-17)21(27)9-15-6-8-25(11-15)14-22/h3-5,7,10,15,17H,6,8-9,11-13H2,1-2H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498863 ((S)-3-(2-(3-(4-Methoxy-3-(1H-pyrazol-5-yl)phenyl)a...) Show SMILES COc1ccc(cc1-c1ccnn1C(=O)OC(C)(C)C)C1CN(C1)C(=O)C[C@@H]1CCN(C1)C(=O)OC(C)(C)C |r| Show InChI InChI=1S/C29H40N4O6/c1-28(2,3)38-26(35)31-13-11-19(16-31)14-25(34)32-17-21(18-32)20-8-9-24(37-7)22(15-20)23-10-12-30-33(23)27(36)39-29(4,5)6/h8-10,12,15,19,21H,11,13-14,16-18H2,1-7H3/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498862 (US11014912, Example 38) Show SMILES COc1ccc(cc1)C1CN(C1)C(=O)C[C@@H]1CCN(C1)C#N Show InChI InChI=1S/C17H21N3O2/c1-22-16-4-2-14(3-5-16)15-10-20(11-15)17(21)8-13-6-7-19(9-13)12-18/h2-5,13,15H,6-11H2,1H3/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498890 (US11014912, Example 68) Show SMILES COc1cccc(C2CN(C2)C(=O)C[C@@H]2CCN(C2)C#N)c1F Show InChI InChI=1S/C17H20FN3O2/c1-23-15-4-2-3-14(17(15)18)13-9-21(10-13)16(22)7-12-5-6-20(8-12)11-19/h2-4,12-13H,5-10H2,1H3/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498877 (US11014912, Example 53) Show SMILES C[C@H]([C@@H]1CCN(C1)C#N)C(=O)Nc1cc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C17H17ClN4O2/c1-11(13-5-6-22(9-13)10-19)17(23)20-16-8-15(21-24-16)12-3-2-4-14(18)7-12/h2-4,7-8,11,13H,5-6,9H2,1H3,(H,20,23)/t11-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498825 (US11014912, Example 1) Show SMILES COc1ccc(cc1)C1CN(C1)C(=O)CC1CCN(C1)C#N Show InChI InChI=1S/C17H21N3O2/c1-22-16-4-2-14(3-5-16)15-10-20(11-15)17(21)8-13-6-7-19(9-13)12-18/h2-5,13,15H,6-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498826 (N-(3-Chlorophenyl)-2-(1- cyanopyrrolidin-3-yl)acet...) Show SMILES Clc1cccc(NC(=O)CC2CCN(C2)C#N)c1 Show InChI InChI=1S/C13H14ClN3O/c14-11-2-1-3-12(7-11)16-13(18)6-10-4-5-17(8-10)9-15/h1-3,7,10H,4-6,8H2,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498827 (2-(1-Cyanopyrrolidin-3-yl)-N-(6- methoxybenzo[d]th...) Show SMILES COc1ccc2nc(NC(=O)CC3CCN(C3)C#N)sc2c1 Show InChI InChI=1S/C15H16N4O2S/c1-21-11-2-3-12-13(7-11)22-15(17-12)18-14(20)6-10-4-5-19(8-10)9-16/h2-3,7,10H,4-6,8H2,1H3,(H,17,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498829 (N-(6-Chlorobenzo[d]thiazol-2- yl)-2-(1-cyanopyrrol...) Show SMILES Clc1ccc2nc(NC(=O)CC3CCN(C3)C#N)sc2c1 Show InChI InChI=1S/C14H13ClN4OS/c15-10-1-2-11-12(6-10)21-14(17-11)18-13(20)5-9-3-4-19(7-9)8-16/h1-2,6,9H,3-5,7H2,(H,17,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498830 (2-(1-Cyanopyrrolidin-3-yl)-N-(3- phenylisoxazol-5-...) Show SMILES O=C(CC1CCN(C1)C#N)Nc1cc(no1)-c1ccccc1 Show InChI InChI=1S/C16H16N4O2/c17-11-20-7-6-12(10-20)8-15(21)18-16-9-14(19-22-16)13-4-2-1-3-5-13/h1-5,9,12H,6-8,10H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498831 (2-(1-Cyanopyrrolidin-3-yl)-N-(5- phenylpyrrolidin-...) Show SMILES O=C(CC1CCN(C1)C#N)NC1CCC(N1)c1ccccc1 Show InChI InChI=1S/C17H22N4O/c18-12-21-9-8-13(11-21)10-17(22)20-16-7-6-15(19-16)14-4-2-1-3-5-14/h1-5,13,15-16,19H,6-11H2,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498832 (N-(5-Chlorobenzo[d]oxazol-2- yl)-2-(1-cyanopyrroli...) Show SMILES Clc1ccc2oc(NC(=O)CC3CCN(C3)C#N)nc2c1 Show InChI InChI=1S/C14H13ClN4O2/c15-10-1-2-12-11(6-10)17-14(21-12)18-13(20)5-9-3-4-19(7-9)8-16/h1-2,6,9H,3-5,7H2,(H,17,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498833 (2-(1-Cyanopyrrolidin-3-yl)-N- (3,4-dichlorophenyl)...) Show SMILES Clc1ccc(NC(=O)CC2CCN(C2)C#N)cc1Cl Show InChI InChI=1S/C13H13Cl2N3O/c14-11-2-1-10(6-12(11)15)17-13(19)5-9-3-4-18(7-9)8-16/h1-2,6,9H,3-5,7H2,(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498834 (2-(1- Cyanopyrrolidin-3- yl)-N-(5- phenylthiazol-2...) Show SMILES O=C(CC1CCN(C1)C#N)Nc1ncc(s1)-c1ccccc1 Show InChI InChI=1S/C16H16N4OS/c17-11-20-7-6-12(10-20)8-15(21)19-16-18-9-14(22-16)13-4-2-1-3-5-13/h1-5,9,12H,6-8,10H2,(H,18,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498836 (3-(2-Oxo-2-(3- phenoxyazetidin-1- yl)ethyl)pyrroli...) Show SMILES O=C(CC1CCN(C1)C#N)N1CC(C1)Oc1ccccc1 Show InChI InChI=1S/C16H19N3O2/c17-12-18-7-6-13(9-18)8-16(20)19-10-15(11-19)21-14-4-2-1-3-5-14/h1-5,13,15H,6-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498837 (3-(2-(3-(3- Methoxyphenyl) azetidin-1-yl)-2- oxoet...) Show SMILES COc1cccc(c1)C1CN(C1)C(=O)CC1CCN(C1)C#N Show InChI InChI=1S/C17H21N3O2/c1-22-16-4-2-3-14(8-16)15-10-20(11-15)17(21)7-13-5-6-19(9-13)12-18/h2-4,8,13,15H,5-7,9-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498838 (2-(1- Cyanopyrrolidin-3- yl)-N-(3,4- dichloropheny...) Show SMILES Fc1ccc(cc1F)C1CN(C1)C(=O)CC1CCN(C1)C#N Show InChI InChI=1S/C16H17F2N3O/c17-14-2-1-12(6-15(14)18)13-8-21(9-13)16(22)5-11-3-4-20(7-11)10-19/h1-2,6,11,13H,3-5,7-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498841 (US11014912, Example 17) Show SMILES COc1ccc(cc1)C1CN(C1)C(=O)C=C1CCN(C1)C#N |w:14.15| Show InChI InChI=1S/C17H19N3O2/c1-22-16-4-2-14(3-5-16)15-10-20(11-15)17(21)8-13-6-7-19(9-13)12-18/h2-5,8,15H,6-7,9-11H2,1H3/b13-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498842 (3-(2-Oxo-2-(3-phenylazetidin-1-yl)ethylidene)pyrro...) Show SMILES O=C(C=C1CCN(C1)C#N)N1CC(C1)c1ccccc1 Show InChI InChI=1S/C16H17N3O/c17-12-18-7-6-13(9-18)8-16(20)19-10-15(11-19)14-4-2-1-3-5-14/h1-5,8,15H,6-7,9-11H2/b13-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498843 (N-(3-Chloro-4-methylphenyl)- 2-(1-cyanopyrrolidin-...) Show SMILES Cc1ccc(NC(=O)C=C2CCN(C2)C#N)cc1Cl |w:8.7| Show InChI InChI=1S/C14H14ClN3O/c1-10-2-3-12(7-13(10)15)17-14(19)6-11-4-5-18(8-11)9-16/h2-3,6-7H,4-5,8H2,1H3,(H,17,19)/b11-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498844 (N-(4-Chloro-3- (trifluoromethyl)phenyl)-2-(1- cyan...) Show SMILES FC(F)(F)c1cc(NC(=O)C=C2CCN(C2)C#N)ccc1Cl |w:10.9| Show InChI InChI=1S/C14H11ClF3N3O/c15-12-2-1-10(6-11(12)14(16,17)18)20-13(22)5-9-3-4-21(7-9)8-19/h1-2,5-6H,3-4,7H2,(H,20,22)/b9-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498847 (2-(1-Cyanopyrrolidin-3- ylidene)-N-(quinolin-3- yl...) Show SMILES O=C(Nc1cnc2ccccc2c1)C=C1CCN(C1)C#N |w:13.14| Show InChI InChI=1S/C16H14N4O/c17-11-20-6-5-12(10-20)7-16(21)19-14-8-13-3-1-2-4-15(13)18-9-14/h1-4,7-9H,5-6,10H2,(H,19,21)/b12-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498848 (2-(1-Cyanopyrrolidin-3- ylidene)-N-methyl-N-(quino...) Show SMILES CN(Cc1ccc2ncccc2c1)C(=O)C=C1CCN(C1)C#N |w:15.16| Show InChI InChI=1S/C18H18N4O/c1-21(18(23)10-15-6-8-22(12-15)13-19)11-14-4-5-17-16(9-14)3-2-7-20-17/h2-5,7,9-10H,6,8,11-12H2,1H3/b15-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498849 (2-(1-Cyanopyrrolidin-3- ylidene)-N-methyl-N-((5- p...) Show SMILES CN(Cc1cc(on1)-c1ccccc1)C(=O)C=C1CCN(C1)C#N |w:16.17| Show InChI InChI=1S/C18H18N4O2/c1-21(18(23)9-14-7-8-22(11-14)13-19)12-16-10-17(24-20-16)15-5-3-2-4-6-15/h2-6,9-10H,7-8,11-12H2,1H3/b14-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498850 (2-(1-Cyanopyrrolidin-3- ylidene)-N-methyl-N-(3- (p...) Show SMILES CN(Cc1cccc(c1)-c1ccncc1)C(=O)C=C1CCN(C1)C#N |w:17.18| Show InChI InChI=1S/C20H20N4O/c1-23(20(25)12-17-7-10-24(14-17)15-21)13-16-3-2-4-19(11-16)18-5-8-22-9-6-18/h2-6,8-9,11-12H,7,10,13-14H2,1H3/b17-12-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498851 (2-(1-Cyanopyrrolidin-3- ylidene)-N-methyl-N-((3- p...) Show SMILES CN(Cc1cc(no1)-c1ccccc1)C(=O)C=C1CCN(C1)C#N |w:16.17| Show InChI InChI=1S/C18H18N4O2/c1-21(18(23)9-14-7-8-22(11-14)13-19)12-16-10-17(20-24-16)15-5-3-2-4-6-15/h2-6,9-10H,7-8,11-12H2,1H3/b14-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498852 (2-(1-Cyanopyrrolidin-3- ylidene)-N-methyl-N-(4- (p...) Show SMILES CN(Cc1ccc(cc1)N1CCCC1)C(=O)C=C1CCN(C1)C#N |w:16.17| Show InChI InChI=1S/C19H24N4O/c1-21(19(24)12-17-8-11-22(14-17)15-20)13-16-4-6-18(7-5-16)23-9-2-3-10-23/h4-7,12H,2-3,8-11,13-14H2,1H3/b17-12-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498853 (2-(1-Cyanopyrrolidin-3- ylidene)-N-methyl-((2- phe...) Show SMILES CNC(=O)C(Cc1csc(n1)-c1ccccc1)=C1CCN(C1)C#N |w:17.23| Show InChI InChI=1S/C18H18N4OS/c1-20-17(23)16(14-7-8-22(10-14)12-19)9-15-11-24-18(21-15)13-5-3-2-4-6-13/h2-6,11H,7-10H2,1H3,(H,20,23)/b16-14-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498854 (2-(1-Cyanopyrrolidin-3- ylidene)-N-methyl-N-((5- p...) Show SMILES CN(Cc1cc(n[nH]1)-c1ccccc1)C(=O)C=C1CCN(C1)C#N |w:16.17| Show InChI InChI=1S/C18H19N5O/c1-22(18(24)9-14-7-8-23(11-14)13-19)12-16-10-17(21-20-16)15-5-3-2-4-6-15/h2-6,9-10H,7-8,11-12H2,1H3,(H,20,21)/b14-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498856 (N-(Benzo[d]thiazol-2-yl)-2-(1- cyanopyrrolidin-3-y...) Show SMILES CN(C(=O)C=C1CCN(C1)C#N)c1nc2ccccc2s1 |w:4.3| Show InChI InChI=1S/C15H14N4OS/c1-18(14(20)8-11-6-7-19(9-11)10-16)15-17-12-4-2-3-5-13(12)21-15/h2-5,8H,6-7,9H2,1H3/b11-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498857 (2-(1-Cyanopyrrolidin-3- ylidene)-N-(3,4- dichlorob...) Show SMILES CN(Cc1ccc(Cl)c(Cl)c1)C(=O)C=C1CCN(C1)C#N |w:13.13| Show InChI InChI=1S/C15H15Cl2N3O/c1-19(8-11-2-3-13(16)14(17)6-11)15(21)7-12-4-5-20(9-12)10-18/h2-3,6-7H,4-5,8-9H2,1H3/b12-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498858 ((S)—N-(3-(4-Chlorophenyl)isoxazol-5-yl)-2-(1-...) Show SMILES Clc1ccc(cc1)-c1cc(NC(=O)C[C@@H]2CCN(C2)C#N)on1 |r| Show InChI InChI=1S/C16H15ClN4O2/c17-13-3-1-12(2-4-13)14-8-16(23-20-14)19-15(22)7-11-5-6-21(9-11)10-18/h1-4,8,11H,5-7,9H2,(H,19,22)/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498859 ((R)—N-(3-(4-Chlorophenyl)isoxazol-5-yl)-2-(1-...) Show SMILES Clc1ccc(cc1)-c1cc(NC(=O)C[C@H]2CCN(C2)C#N)on1 |r| Show InChI InChI=1S/C16H15ClN4O2/c17-13-3-1-12(2-4-13)14-8-16(23-20-14)19-15(22)7-11-5-6-21(9-11)10-18/h1-4,8,11H,5-7,9H2,(H,19,22)/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498861 ((S)—N-(3-(3-Methoxyphenyl)isoxazol-5-yl)-2-(1...) Show SMILES COc1cccc(c1)-c1cc(NC(=O)C[C@@H]2CCN(C2)C#N)on1 |r| Show InChI InChI=1S/C17H18N4O3/c1-23-14-4-2-3-13(8-14)15-9-17(24-20-15)19-16(22)7-12-5-6-21(10-12)11-18/h2-4,8-9,12H,5-7,10H2,1H3,(H,19,22)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498865 (US11014912, Example 41) Show SMILES O=C(CC1CCN(C1)C#N)Nc1nnc(s1)-c1ccccc1 Show InChI InChI=1S/C15H15N5OS/c16-10-20-7-6-11(9-20)8-13(21)17-15-19-18-14(22-15)12-4-2-1-3-5-12/h1-5,11H,6-9H2,(H,17,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498869 (US11014912, Example 45) Show SMILES FC(F)(F)c1ccnc(NC(=O)CC2CCN(C2)C#N)c1 Show InChI InChI=1S/C13H13F3N4O/c14-13(15,16)10-1-3-18-11(6-10)19-12(21)5-9-2-4-20(7-9)8-17/h1,3,6,9H,2,4-5,7H2,(H,18,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498871 (US11014912, Example 47) Show SMILES O=C(CC1CCN(C1)C#N)NC1CN(C1)c1ccccn1 Show InChI InChI=1S/C15H19N5O/c16-11-19-6-4-12(8-19)7-15(21)18-13-9-20(10-13)14-3-1-2-5-17-14/h1-3,5,12-13H,4,6-10H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498872 (US11014912, Example 48) Show SMILES Clc1cccc(c1)-c1nnc(NC(=O)C[C@@H]2CCN(C2)C#N)o1 Show InChI InChI=1S/C15H14ClN5O2/c16-12-3-1-2-11(7-12)14-19-20-15(23-14)18-13(22)6-10-4-5-21(8-10)9-17/h1-3,7,10H,4-6,8H2,(H,18,20,22)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498873 (US11014912, Example 49) Show SMILES O=C(CC1CCN(C1)C#N)Nc1nnc(o1)-c1cccc(c1)C#N Show InChI InChI=1S/C16H14N6O2/c17-8-11-2-1-3-13(6-11)15-20-21-16(24-15)19-14(23)7-12-4-5-22(9-12)10-18/h1-3,6,12H,4-5,7,9H2,(H,19,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM498876 (US11014912, Example 52) Show SMILES O=C(C[C@@H]1CCN(C1)C#N)N1CC(C1)c1ccc(cc1)C#N Show InChI InChI=1S/C17H18N4O/c18-8-13-1-3-15(4-2-13)16-10-21(11-16)17(22)7-14-5-6-20(9-14)12-19/h1-4,14,16H,5-7,9-11H2/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US11014912 (2021) BindingDB Entry DOI: 10.7270/Q2ZW1Q27
					More data for this Ligand-Target Pair

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