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Found 1 hit Enz. Inhib. hit(s) with Target = '1,3-beta-D-glucan synthase catalytic subunit' and Ligand = 'BDBM50483449'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1,3-beta-D-glucan synthase catalytic subunit


(Candida albicans)		BDBM50483449
PNG
(CHEMBL1684882)
Show SMILES O=c1c(OC2CCCC2)c(cnn1-c1ccccc1)N1CCN(CC1)S(=O)(=O)Cc1cccnc1
Show InChI InChI=1S/C25H29N5O4S/c31-25-24(34-22-10-4-5-11-22)23(18-27-30(25)21-8-2-1-3-9-21)28-13-15-29(16-14-28)35(32,33)19-20-7-6-12-26-17-20/h1-3,6-9,12,17-18,22H,4-5,10-11,13-16,19H2
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 403n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans BWP17 1,3-beta-D-glucan synthase

Bioorg Med Chem Lett 21: 1819-22 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.058
BindingDB Entry DOI: 10.7270/Q2P55RCG
More data for this
Ligand-Target Pair