BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '1,3-beta-D-glucan synthase catalytic subunit' and Ligand = 'BDBM50483475'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1,3-beta-D-glucan synthase catalytic subunit


(Candida albicans)		BDBM50483475
PNG
(CHEMBL1684895)
Show SMILES CC(C)S(=O)(=O)N1CCN(CC1)c1cnn(-c2cccc(F)c2)c(=O)c1OC1CCC(F)C1
Show InChI InChI=1S/C22H28F2N4O4S/c1-15(2)33(30,31)27-10-8-26(9-11-27)20-14-25-28(18-5-3-4-16(23)12-18)22(29)21(20)32-19-7-6-17(24)13-19/h3-5,12,14-15,17,19H,6-11,13H2,1-2H3
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 870n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans BWP17 1,3-beta-D-glucan synthase

Bioorg Med Chem Lett 21: 1819-22 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.058
BindingDB Entry DOI: 10.7270/Q2P55RCG
More data for this
Ligand-Target Pair