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Found 1 hit Enz. Inhib. hit(s) with Target = '1,3-beta-D-glucan synthase catalytic subunit' and Ligand = 'BDBM50485317'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1,3-beta-D-glucan synthase catalytic subunit


(Candida albicans)		BDBM50485317
PNG
(CHEMBL2046598)
Show SMILES CCN(CC)S(=O)(=O)N1CCN(CC1)C(\C=N)=C(/OC1CCCC1)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C23H34ClN5O4S/c1-3-28(4-2)34(31,32)29-14-12-27(13-15-29)21(17-25)22(33-20-10-5-6-11-20)23(30)26-19-9-7-8-18(24)16-19/h7-9,16-17,20,25H,3-6,10-15H2,1-2H3,(H,26,30)/b22-21-,25-17?
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 624n/an/an/an/an/an/a



Albany Molecular Research, Inc. (AMRI)

Curated by ChEMBL


Assay Description
Inhibition of glucan synthase in Candida albicans BWP17 membrane

Bioorg Med Chem Lett 22: 4896-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.127
BindingDB Entry DOI: 10.7270/Q2NC6424
More data for this
Ligand-Target Pair