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Found 2 hits Enz. Inhib. hit(s) with Target = '1-acyl-sn-glycerol-3-phosphate acyltransferase beta' and Ligand = 'BDBM50141287'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1-acyl-sn-glycerol-3-phosphate acyltransferase beta


(Homo sapiens (Human))		BDBM50141287
PNG
(5TT4A4MBLR | CHEMBL36501 | CT 32228 | CT-32228 | H...)
Show SMILES Cc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(Br)cc2)n1
Show InChI InChI=1S/C16H13BrClN5/c1-9-2-5-11(18)8-13(9)14-21-15(19)23-16(22-14)20-12-6-3-10(17)4-7-12/h2-8H,1H3,(H3,19,20,21,22,23)
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n/an/a 60n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114645
BindingDB Entry DOI: 10.7270/Q2SQ94GB
More data for this
Ligand-Target Pair
1-acyl-sn-glycerol-3-phosphate acyltransferase beta


(Homo sapiens (Human))		BDBM50141287
PNG
(5TT4A4MBLR | CHEMBL36501 | CT 32228 | CT-32228 | H...)
Show SMILES Cc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(Br)cc2)n1
Show InChI InChI=1S/C16H13BrClN5/c1-9-2-5-11(18)8-13(9)14-21-15(19)23-16(22-14)20-12-6-3-10(17)4-7-12/h2-8H,1H3,(H3,19,20,21,22,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes

Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair