Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM108094'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM108094 (US8598163, 6) Show SMILES CC(C)(O)C[C@@]1(CCN([C@H]2CCCN(C2)c2ccc3ncnn3c2)C(=O)O1)c1ccccc1 |r| Show InChI InChI=1S/C25H31N5O3/c1-24(2,32)17-25(19-7-4-3-5-8-19)12-14-29(23(31)33-25)21-9-6-13-28(15-21)20-10-11-22-26-18-27-30(22)16-20/h3-5,7-8,10-11,16,18,21,32H,6,9,12-15,17H2,1-2H3/t21-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	7.4	n/a
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...				US Patent US8598163 (2013) BindingDB Entry DOI: 10.7270/Q29K48WR
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