Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM142006'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM142006 (US8927536, 81) Show SMILES Cn1cc(cn1)-c1ccc(c(F)c1)C1(CC1)c1nnc2C[C@](C)(CO)SCCn12 |r| Show InChI InChI=1S/C21H24FN5OS/c1-20(13-28)10-18-24-25-19(27(18)7-8-29-20)21(5-6-21)16-4-3-14(9-17(16)22)15-11-23-26(2)12-15/h3-4,9,11-12,28H,5-8,10,13H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.4	25
Daiichi Sankyo Company, Limited US Patent					Assay Description A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 µL, and all the samples were diluted with an assay buffe...				US Patent US8927536 (2015) BindingDB Entry DOI: 10.7270/Q2Q23XZP
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