Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50193784'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50193784 (4-[4-(4-imidazol-1-yl-phenoxymethyl)-3,3-dimethyl-...) Show SMILES CC1(C)C(COc2ccc(cc2)-n2ccnc2)CN([C@H]2C3CC4CC2C[C@](C4)(C3)C(N)=O)C1=O |wU:19.20,wD:26.33,TLB:19:20:27:23.24.25,18:19:27.22.23:25,THB:21:22:25:28.20.19,21:20:27.22.23:25,19:24:27:28.21.20,(8.91,-1.06,;7.59,-.29,;8.04,1.18,;7.11,-1.75,;8.02,-3,;9.56,-2.97,;10.36,-4.29,;9.61,-5.63,;10.41,-6.95,;11.95,-6.92,;12.7,-5.56,;11.89,-4.25,;12.74,-8.23,;12.15,-9.65,;13.31,-10.65,;14.63,-9.85,;14.27,-8.36,;5.56,-1.75,;5.09,-.29,;3.63,.18,;2.31,-.4,;.78,.19,;.72,1.72,;2.17,2.25,;3.63,1.72,;2.64,2.9,;1.2,2.31,;-.22,2.94,;1.32,.78,;1.19,3.86,;-.15,4.62,;2.52,4.64,;6.34,.62,;6.34,2.16,)| Show InChI InChI=1S/C27H34N4O3/c1-26(2)20(15-34-22-5-3-21(4-6-22)30-8-7-29-16-30)14-31(25(26)33)23-18-9-17-10-19(23)13-27(11-17,12-18)24(28)32/h3-8,16-20,23H,9-15H2,1-2H3,(H2,28,32)/t17?,18?,19?,20?,23-,27-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells				Bioorg Med Chem Lett 16: 5555-60 (2006) Article DOI: 10.1016/j.bmcl.2006.08.034 BindingDB Entry DOI: 10.7270/Q25X28K5
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50193784 (4-[4-(4-imidazol-1-yl-phenoxymethyl)-3,3-dimethyl-...) Show SMILES CC1(C)C(COc2ccc(cc2)-n2ccnc2)CN([C@H]2C3CC4CC2C[C@](C4)(C3)C(N)=O)C1=O |wU:19.20,wD:26.33,TLB:19:20:27:23.24.25,18:19:27.22.23:25,THB:21:22:25:28.20.19,21:20:27.22.23:25,19:24:27:28.21.20,(8.91,-1.06,;7.59,-.29,;8.04,1.18,;7.11,-1.75,;8.02,-3,;9.56,-2.97,;10.36,-4.29,;9.61,-5.63,;10.41,-6.95,;11.95,-6.92,;12.7,-5.56,;11.89,-4.25,;12.74,-8.23,;12.15,-9.65,;13.31,-10.65,;14.63,-9.85,;14.27,-8.36,;5.56,-1.75,;5.09,-.29,;3.63,.18,;2.31,-.4,;.78,.19,;.72,1.72,;2.17,2.25,;3.63,1.72,;2.64,2.9,;1.2,2.31,;-.22,2.94,;1.32,.78,;1.19,3.86,;-.15,4.62,;2.52,4.64,;6.34,.62,;6.34,2.16,)| Show InChI InChI=1S/C27H34N4O3/c1-26(2)20(15-34-22-5-3-21(4-6-22)30-8-7-29-16-30)14-31(25(26)33)23-18-9-17-10-19(23)13-27(11-17,12-18)24(28)32/h3-8,16-20,23H,9-15H2,1-2H3,(H2,28,32)/t17?,18?,19?,20?,23-,27-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				Bioorg Med Chem Lett 16: 5555-60 (2006) Article DOI: 10.1016/j.bmcl.2006.08.034 BindingDB Entry DOI: 10.7270/Q25X28K5
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50193784 (4-[4-(4-imidazol-1-yl-phenoxymethyl)-3,3-dimethyl-...) Show SMILES CC1(C)C(COc2ccc(cc2)-n2ccnc2)CN([C@H]2C3CC4CC2C[C@](C4)(C3)C(N)=O)C1=O |wU:19.20,wD:26.33,TLB:19:20:27:23.24.25,18:19:27.22.23:25,THB:21:22:25:28.20.19,21:20:27.22.23:25,19:24:27:28.21.20,(8.91,-1.06,;7.59,-.29,;8.04,1.18,;7.11,-1.75,;8.02,-3,;9.56,-2.97,;10.36,-4.29,;9.61,-5.63,;10.41,-6.95,;11.95,-6.92,;12.7,-5.56,;11.89,-4.25,;12.74,-8.23,;12.15,-9.65,;13.31,-10.65,;14.63,-9.85,;14.27,-8.36,;5.56,-1.75,;5.09,-.29,;3.63,.18,;2.31,-.4,;.78,.19,;.72,1.72,;2.17,2.25,;3.63,1.72,;2.64,2.9,;1.2,2.31,;-.22,2.94,;1.32,.78,;1.19,3.86,;-.15,4.62,;2.52,4.64,;6.34,.62,;6.34,2.16,)| Show InChI InChI=1S/C27H34N4O3/c1-26(2)20(15-34-22-5-3-21(4-6-22)30-8-7-29-16-30)14-31(25(26)33)23-18-9-17-10-19(23)13-27(11-17,12-18)24(28)32/h3-8,16-20,23H,9-15H2,1-2H3,(H2,28,32)/t17?,18?,19?,20?,23-,27-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				Bioorg Med Chem Lett 16: 5555-60 (2006) Article DOI: 10.1016/j.bmcl.2006.08.034 BindingDB Entry DOI: 10.7270/Q25X28K5
					More data for this Ligand-Target Pair