Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50249527 (CHEMBL470533 | ethyl 5-(2,5-dimethylphenylsulfonam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica Curated by ChEMBL | Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in... | Eur J Med Chem 44: 1167-71 (2009) Article DOI: 10.1016/j.ejmech.2008.06.005 BindingDB Entry DOI: 10.7270/Q2251J0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse)) | BDBM50249527 (CHEMBL470533 | ethyl 5-(2,5-dimethylphenylsulfonam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica Curated by ChEMBL | Assay Description Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in... | Eur J Med Chem 44: 1167-71 (2009) Article DOI: 10.1016/j.ejmech.2008.06.005 BindingDB Entry DOI: 10.7270/Q2251J0Z | |||||||||||
More data for this Ligand-Target Pair |