Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50297916'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297916 (2-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccccc2Cl)cc1 |r| Show InChI InChI=1S/C20H23ClN2O4S/c1-14-12-23(13-15(2)27-14)20(24)17-9-7-16(8-10-17)11-22-28(25,26)19-6-4-3-5-18(19)21/h3-10,14-15,22H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297916 (2-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccccc2Cl)cc1 |r| Show InChI InChI=1S/C20H23ClN2O4S/c1-14-12-23(13-15(2)27-14)20(24)17-9-7-16(8-10-17)11-22-28(25,26)19-6-4-3-5-18(19)21/h3-10,14-15,22H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair