Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50306425'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50306425 (2-{1'-[(adamantan-2-yl)carbamoyl]-7-methyl-2,3-dih...) Show SMILES Cc1cccc2C(CC(O)=O)CC3(CCN(CC3)C(=O)NC3C4CC5CC(C4)CC3C5)c12 |TLB:27:26:30:23.22.21,27:22:25.26.28:30,THB:21:22:25:28.29.30,21:29:25:23.27.22,20:21:25.26.28:30,(38.07,-13.73,;39.3,-12.81,;40.71,-13.41,;41.94,-12.48,;41.75,-10.96,;40.34,-10.37,;39.84,-8.91,;40.62,-7.57,;42.16,-7.57,;42.93,-8.91,;42.94,-6.23,;38.3,-8.94,;37.85,-10.41,;37.8,-11.95,;36.44,-12.68,;35.13,-11.87,;35.16,-10.33,;36.53,-9.6,;33.78,-12.61,;33.73,-14.15,;32.46,-11.8,;31.1,-12.54,;31.09,-14.07,;29.69,-14.42,;28.37,-13.92,;27.17,-15.2,;28.66,-14.78,;30.07,-15.35,;28.66,-13.19,;29.7,-11.96,;28.35,-12.44,;39.12,-11.29,)| Show InChI InChI=1S/C27H36N2O3/c1-16-3-2-4-22-21(14-23(30)31)15-27(24(16)22)5-7-29(8-6-27)26(32)28-25-19-10-17-9-18(12-19)13-20(25)11-17/h2-4,17-21,25H,5-15H2,1H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol by SPA				Bioorg Med Chem Lett 20: 881-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.082 BindingDB Entry DOI: 10.7270/Q2KK9BWZ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50306425 (2-{1'-[(adamantan-2-yl)carbamoyl]-7-methyl-2,3-dih...) Show SMILES Cc1cccc2C(CC(O)=O)CC3(CCN(CC3)C(=O)NC3C4CC5CC(C4)CC3C5)c12 |TLB:27:26:30:23.22.21,27:22:25.26.28:30,THB:21:22:25:28.29.30,21:29:25:23.27.22,20:21:25.26.28:30,(38.07,-13.73,;39.3,-12.81,;40.71,-13.41,;41.94,-12.48,;41.75,-10.96,;40.34,-10.37,;39.84,-8.91,;40.62,-7.57,;42.16,-7.57,;42.93,-8.91,;42.94,-6.23,;38.3,-8.94,;37.85,-10.41,;37.8,-11.95,;36.44,-12.68,;35.13,-11.87,;35.16,-10.33,;36.53,-9.6,;33.78,-12.61,;33.73,-14.15,;32.46,-11.8,;31.1,-12.54,;31.09,-14.07,;29.69,-14.42,;28.37,-13.92,;27.17,-15.2,;28.66,-14.78,;30.07,-15.35,;28.66,-13.19,;29.7,-11.96,;28.35,-12.44,;39.12,-11.29,)| Show InChI InChI=1S/C27H36N2O3/c1-16-3-2-4-22-21(14-23(30)31)15-27(24(16)22)5-7-29(8-6-27)26(32)28-25-19-10-17-9-18(12-19)13-20(25)11-17/h2-4,17-21,25H,5-15H2,1H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18.3	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human adipocytes assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by SPA				Bioorg Med Chem Lett 20: 881-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.082 BindingDB Entry DOI: 10.7270/Q2KK9BWZ
					More data for this Ligand-Target Pair