Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50354746'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50354746 (CHEMBL1834085) Show SMILES CN(Cc1ccccc1)S(=O)(=O)c1ccc(Oc2cccc(Cl)c2C#N)cc1 Show InChI InChI=1S/C21H17ClN2O3S/c1-24(15-16-6-3-2-4-7-16)28(25,26)18-12-10-17(11-13-18)27-21-9-5-8-20(22)19(21)14-23/h2-13H,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	41.3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceutical Holding Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...				Bioorg Med Chem Lett 21: 5739-44 (2011) Article DOI: 10.1016/j.bmcl.2011.08.019 BindingDB Entry DOI: 10.7270/Q27H1K0C
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