Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50390712'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50390712 (CHEMBL2070321) Show SMILES Fc1ccc(cc1)C1(CC1)C(=O)N1CCC(C1)c1c[nH]c2cnccc12 Show InChI InChI=1S/C21H20FN3O/c22-16-3-1-15(2-4-16)21(7-8-21)20(26)25-10-6-14(13-25)18-11-24-19-12-23-9-5-17(18)19/h1-5,9,11-12,14,24H,6-8,10,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Merck-Serono S.A. Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...				Bioorg Med Chem Lett 22: 5909-14 (2012) Article DOI: 10.1016/j.bmcl.2012.07.070 BindingDB Entry DOI: 10.7270/Q2Z89DH5
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