Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50400173'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50400173 (CHEMBL2179020) Show SMILES O[C@@]12CC3CC(C1)[C@H](NC(=O)c1cnc(NC4CCS(=O)(=O)CC4)nc1C1CCCC1)C(C3)C2 |r,wU:7.8,wD:1.0,TLB:0:1:7:32.3.4,8:7:6.33.1:32.3.4,8:7:4:6.1.2,THB:0:1:7.31.32:4,2:1:7:32.3.4,2:3:7:6.33.1,33:31:4:6.1.2,33:1:7.31.32:4,(74.15,-51.19,;72.62,-51.17,;71.58,-50.05,;70.16,-50.6,;69.51,-51.87,;70.54,-52.95,;71.84,-52.39,;70.55,-54.69,;69.22,-55.47,;67.88,-54.7,;67.88,-53.16,;66.55,-55.48,;65.22,-54.71,;63.89,-55.48,;63.89,-57.03,;62.55,-57.8,;61.22,-57.03,;61.23,-55.49,;59.9,-54.72,;58.56,-55.48,;57.06,-55.87,;57.46,-54.38,;58.56,-57.02,;59.89,-57.8,;65.22,-57.8,;66.56,-57.03,;67.89,-57.8,;68.06,-59.32,;69.57,-59.64,;70.33,-58.3,;69.3,-57.16,;71.35,-53.36,;70.18,-52.04,;72.77,-52.8,)| Show InChI InChI=1S/C25H36N4O4S/c30-23(28-21-17-9-15-10-18(21)13-25(31,11-15)12-17)20-14-26-24(29-22(20)16-3-1-2-4-16)27-19-5-7-34(32,33)8-6-19/h14-19,21,31H,1-13H2,(H,28,30)(H,26,27,29)/t15?,17?,18?,21-,25-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 by HTRF assay				J Med Chem 55: 10652-61 (2012) Article DOI: 10.1021/jm3013163 BindingDB Entry DOI: 10.7270/Q2BG2Q4S
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50400173 (CHEMBL2179020) Show SMILES O[C@@]12CC3CC(C1)[C@H](NC(=O)c1cnc(NC4CCS(=O)(=O)CC4)nc1C1CCCC1)C(C3)C2 |r,wU:7.8,wD:1.0,TLB:0:1:7:32.3.4,8:7:6.33.1:32.3.4,8:7:4:6.1.2,THB:0:1:7.31.32:4,2:1:7:32.3.4,2:3:7:6.33.1,33:31:4:6.1.2,33:1:7.31.32:4,(74.15,-51.19,;72.62,-51.17,;71.58,-50.05,;70.16,-50.6,;69.51,-51.87,;70.54,-52.95,;71.84,-52.39,;70.55,-54.69,;69.22,-55.47,;67.88,-54.7,;67.88,-53.16,;66.55,-55.48,;65.22,-54.71,;63.89,-55.48,;63.89,-57.03,;62.55,-57.8,;61.22,-57.03,;61.23,-55.49,;59.9,-54.72,;58.56,-55.48,;57.06,-55.87,;57.46,-54.38,;58.56,-57.02,;59.89,-57.8,;65.22,-57.8,;66.56,-57.03,;67.89,-57.8,;68.06,-59.32,;69.57,-59.64,;70.33,-58.3,;69.3,-57.16,;71.35,-53.36,;70.18,-52.04,;72.77,-52.8,)| Show InChI InChI=1S/C25H36N4O4S/c30-23(28-21-17-9-15-10-18(21)13-25(31,11-15)12-17)20-14-26-24(29-22(20)16-3-1-2-4-16)27-19-5-7-34(32,33)8-6-19/h14-19,21,31H,1-13H2,(H,28,30)(H,26,27,29)/t15?,17?,18?,21-,25-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 by HTRF assay				J Med Chem 55: 10652-61 (2012) Article DOI: 10.1021/jm3013163 BindingDB Entry DOI: 10.7270/Q2BG2Q4S
					More data for this Ligand-Target Pair