Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50445583'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50445583 (CHEMBL3103430) Show SMILES OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)c1ccc(cc1)-c1ccncc1 |TLB:0:1:10.8.7:5,9:8:5:3.2.1,1:2:10:7.6.5,1:6:10:3.9.2,17:10:5:3.2.1,11:10:3.9.2:7.6.5,THB:9:2:10.8.7:5,17:10:3.9.2:7.6.5,11:10:5:3.2.1,(50.71,-36.68,;49.42,-37.53,;49.4,-39.07,;48,-39.41,;46.67,-38.92,;46.67,-37.43,;48.01,-36.95,;46.97,-38.19,;46.97,-39.78,;48.39,-40.35,;45.47,-40.2,;44.13,-39.4,;42.78,-40.15,;41.29,-39.73,;40.43,-41.01,;41.39,-42.23,;42.84,-41.69,;45.46,-41.74,;44.12,-42.5,;44.11,-44.03,;45.44,-44.81,;46.78,-44.04,;46.78,-42.51,;45.43,-46.35,;44.09,-47.12,;44.08,-48.66,;45.42,-49.44,;46.76,-48.67,;46.76,-47.13,)| Show InChI InChI=1S/C23H25N5O/c29-22-16-9-19-11-17(22)12-20(10-16)23(19,13-21-25-27-28-26-21)18-3-1-14(2-4-18)15-5-7-24-8-6-15/h1-8,16-17,19-20,22,29H,9-13H2,(H,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				Bioorg Med Chem Lett 24: 654-60 (2014) Article DOI: 10.1016/j.bmcl.2013.11.066 BindingDB Entry DOI: 10.7270/Q20Z74RF
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50445583 (CHEMBL3103430) Show SMILES OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)c1ccc(cc1)-c1ccncc1 |TLB:0:1:10.8.7:5,9:8:5:3.2.1,1:2:10:7.6.5,1:6:10:3.9.2,17:10:5:3.2.1,11:10:3.9.2:7.6.5,THB:9:2:10.8.7:5,17:10:3.9.2:7.6.5,11:10:5:3.2.1,(50.71,-36.68,;49.42,-37.53,;49.4,-39.07,;48,-39.41,;46.67,-38.92,;46.67,-37.43,;48.01,-36.95,;46.97,-38.19,;46.97,-39.78,;48.39,-40.35,;45.47,-40.2,;44.13,-39.4,;42.78,-40.15,;41.29,-39.73,;40.43,-41.01,;41.39,-42.23,;42.84,-41.69,;45.46,-41.74,;44.12,-42.5,;44.11,-44.03,;45.44,-44.81,;46.78,-44.04,;46.78,-42.51,;45.43,-46.35,;44.09,-47.12,;44.08,-48.66,;45.42,-49.44,;46.76,-48.67,;46.76,-47.13,)| Show InChI InChI=1S/C23H25N5O/c29-22-16-9-19-11-17(22)12-20(10-16)23(19,13-21-25-27-28-26-21)18-3-1-14(2-4-18)15-5-7-24-8-6-15/h1-8,16-17,19-20,22,29H,9-13H2,(H,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				Bioorg Med Chem Lett 24: 654-60 (2014) Article DOI: 10.1016/j.bmcl.2013.11.066 BindingDB Entry DOI: 10.7270/Q20Z74RF
					More data for this Ligand-Target Pair