Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM99300'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99300 (US8497281, 78) Show SMILES C[C@]12CCCN([C@@H]1CCc1ccccc21)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H23N3O/c1-22-11-4-12-25(20(22)10-8-15-5-2-3-6-17(15)22)21(26)16-7-9-18-19(13-16)24-14-23-18/h2-3,5-7,9,13-14,20H,4,8,10-12H2,1H3,(H,23,24)/t20-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
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