Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM99309'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99309 (US8497281, 87) Show SMILES Fc1cc(F)c2CC[C@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c2c1 |r| Show InChI InChI=1S/C21H19F2N3O/c22-13-9-16-14(17(23)10-13)4-6-20-15(16)2-1-7-26(20)21(27)12-3-5-18-19(8-12)25-11-24-18/h3,5,8-11,15,20H,1-2,4,6-7H2,(H,24,25)/t15?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	227	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
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