Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM99316'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99316 (US8497281, 94) Show SMILES Fc1cccc2CC[C@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c12 |r| Show InChI InChI=1S/C21H20FN3O/c22-16-5-1-3-13-7-9-19-15(20(13)16)4-2-10-25(19)21(26)14-6-8-17-18(11-14)24-12-23-17/h1,3,5-6,8,11-12,15,19H,2,4,7,9-10H2,(H,23,24)/t15?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	297	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
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