Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM99463'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99463 (US8497281, 241) Show SMILES Cc1cc2C[C@H]3[C@H](CCCN3C(=O)c3ccc4nc[nH]c4c3)c2cc1C#N |r| Show InChI InChI=1S/C22H20N4O/c1-13-7-15-10-21-17(18(15)8-16(13)11-23)3-2-6-26(21)22(27)14-4-5-19-20(9-14)25-12-24-19/h4-5,7-9,12,17,21H,2-3,6,10H2,1H3,(H,24,25)/t17-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99463 (US8497281, 241) Show SMILES Cc1cc2C[C@H]3[C@H](CCCN3C(=O)c3ccc4nc[nH]c4c3)c2cc1C#N |r| Show InChI InChI=1S/C22H20N4O/c1-13-7-15-10-21-17(18(15)8-16(13)11-23)3-2-6-26(21)22(27)14-4-5-19-20(9-14)25-12-24-19/h4-5,7-9,12,17,21H,2-3,6,10H2,1H3,(H,24,25)/t17-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair