Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
11-beta-hydroxysteroid dehydrogenase 1 [24-292,C272S] (Homo sapiens (Human)) | BDBM32539 (arylsulfonylpiperazine, 11) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 46 | n/a | 667 | n/a | n/a | 7.2 | 22 |
Amgen Inc. | Assay Description Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e... | Bioorg Med Chem Lett 18: 3513-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.025 BindingDB Entry DOI: 10.7270/Q2J964Q1 | |||||||||||
More data for this Ligand-Target Pair |