Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '17-beta-hydroxysteroid dehydrogenase 14' and Ligand = 'BDBM50422423'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase 14 (Homo sapiens (Human))	BDBM50422423 (CHEMBL4160081) Show SMILES Oc1cccc(c1F)-c1cccc(n1)C(=O)Nc1ccc(F)c(O)c1 Show InChI InChI=1S/C34H64N6O3/c1-2-16-33(42)40-32(29-30-17-19-31(41)20-18-30)34(43)39-28-15-27-38-26-14-8-7-13-25-37-24-12-6-5-11-23-36-22-10-4-3-9-21-35/h17-20,32,36-38,41H,2-16,21-29,35H2,1H3,(H,39,43)(H,40,42)/t32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	336	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Binding affinity to recombinant 17beta-HSD14 (unknown origin) expressed in Escherichia coli BL21 pLysS strain using E2 as substrate in presence of NA...				Eur J Med Chem 155: 61-76 (2018) Article DOI: 10.1016/j.ejmech.2018.05.029 BindingDB Entry DOI: 10.7270/Q23F4S76
					More data for this Ligand-Target Pair