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Found 1 hit Enz. Inhib. hit(s) with Target = '17-beta-hydroxysteroid dehydrogenase type 3' and Ligand = 'BDBM50381591'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))		BDBM50381591
PNG
(CHEMBL2018243)
Show SMILES COc1ccc(cc1)N1C(=S)S\C(=C(/C)c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C18H14BrNO3S2/c1-10(11-3-8-15(21)14(19)9-11)16-17(22)20(18(24)25-16)12-4-6-13(23-2)7-5-12/h3-9,21H,1-2H3/b16-10+
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Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...

Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair