Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens) | BDBM50561669![]() (CHEMBL4787939) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens) | BDBM50561669![]() (CHEMBL4787939) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8 | |||||||||||
More data for this Ligand-Target Pair |