Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '26S proteasome non-ATPase regulatory subunit 14' and Ligand = 'BDBM50264423'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264423 (CHEMBL4103171) Show SMILES CNC(=O)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NC)cccc2c1 Show InChI InChI=1S/C22H18N4O2S2/c1-23-21(27)15-9-13-5-3-7-17(19(13)25-11-15)29-30-18-8-4-6-14-10-16(22(28)24-2)12-26-20(14)18/h3-12H,1-2H3,(H,23,27)(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264423 (CHEMBL4103171) Show SMILES CNC(=O)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NC)cccc2c1 Show InChI InChI=1S/C22H18N4O2S2/c1-23-21(27)15-9-13-5-3-7-17(19(13)25-11-15)29-30-18-8-4-6-14-10-16(22(28)24-2)12-26-20(14)18/h3-12H,1-2H3,(H,23,27)(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in beta5 inhibitor MG132 pretreated human HeLa cells expressing UbG76...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair