BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50006411'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-hydroxy-3-methylglutaryl-coenzyme A reductase


(Homo sapiens (Human))		BDBM50006411
PNG
(CHEMBL2367470 | Sodium; 7-[5-(4-fluoro-phenyl)-1-p...)
Show SMILES [Na+].O[C@H](C[C@H](O)\C=C\c1c(nn(c1-c1ccc(F)cc1)-c1ccccn1)C(F)(F)F)CC([O-])=O
Show InChI InChI=1S/C22H19F4N3O4.Na/c23-14-6-4-13(5-7-14)20-17(9-8-15(30)11-16(31)12-19(32)33)21(22(24,25)26)28-29(20)18-3-1-2-10-27-18;/h1-10,15-16,30-31H,11-12H2,(H,32,33);/q;+1/p-1/b9-8+;/t15-,16-;/m1./s1
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 17n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.

J Med Chem 35: 2095-103 (1992)


BindingDB Entry DOI: 10.7270/Q2HH6KN8
More data for this
Ligand-Target Pair