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Found 1 hit Enz. Inhib. hit(s) with Target = '3-oxo-5-alpha-steroid 4-dehydrogenase 1' and Ligand = 'BDBM50070050'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-oxo-5-alpha-steroid 4-dehydrogenase 1


(Homo sapiens (Human))		BDBM50070050
PNG
(2-((4aR,10bR)-4,10b-Dimethyl-3-oxo-1,2,3,4,4a,5,6,...)
Show SMILES CCN(CC)C(=O)Cc1ccc2c(CC[C@H]3N(C)C(=O)CC[C@]23C)c1
Show InChI InChI=1S/C21H30N2O2/c1-5-23(6-2)20(25)14-15-7-9-17-16(13-15)8-10-18-21(17,3)12-11-19(24)22(18)4/h7,9,13,18H,5-6,8,10-12,14H2,1-4H3/t18-,21-/m1/s1
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Similars
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against Steroid 5-alpha-reductase type 1 enzyme based on the conversion of [3H]-T to [3H]-DHT in nuclear membrane preparations fr...

Bioorg Med Chem Lett 8: 395-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CN732C
More data for this
Ligand-Target Pair