Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [51-359]' and Ligand = 'BDBM281766'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [51-359] (Homo sapiens (Human))	BDBM281766 (2-(3-(1H-pyrrolo[2,3-b]pyridin- 3-yl)benzylamino)-...) Show SMILES Fc1ccc(CNC(=O)c2cccnc2NCc2cccc(c2)-c2c[nH]c3ncccc23)cc1F Show InChI InChI=1S/C27H21F2N5O/c28-23-9-8-18(13-24(23)29)15-34-27(35)21-7-3-11-31-26(21)32-14-17-4-1-5-19(12-17)22-16-33-25-20(22)6-2-10-30-25/h1-13,16H,14-15H2,(H,30,33)(H,31,32)(H,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc.; Millenium Pharmaceuticals, Inc. US Patent					Assay Description PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...				US Patent US10030016 (2018) BindingDB Entry DOI: 10.7270/Q2S46V16
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