Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [51-359]' and Ligand = 'BDBM282401'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [51-359] (Homo sapiens (Human))	BDBM282401 (2-(4-(3-amino-1H-pyrazolo [3,4-b]pyridin-5-yl) ben...) Show SMILES Nc1n[nH]c2ncc(cc12)-c1ccc(CNc2ncc(cc2C(=O)NCc2cccc(Cl)c2)C(F)(F)F)cc1 Show InChI InChI=1S/C27H21ClF3N7O/c28-20-3-1-2-16(8-20)12-36-26(39)22-10-19(27(29,30)31)14-35-24(22)33-11-15-4-6-17(7-5-15)18-9-21-23(32)37-38-25(21)34-13-18/h1-10,13-14H,11-12H2,(H,33,35)(H,36,39)(H3,32,34,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc.; Millenium Pharmaceuticals, Inc. US Patent					Assay Description PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...				US Patent US10030016 (2018) BindingDB Entry DOI: 10.7270/Q2S46V16
					More data for this Ligand-Target Pair