Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM327866'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327866 (N2-(1-(4- cyanobenzyl)piperidin-4- yl)-N5-(3- benz...) Show SMILES O=C(NC1CCN(Cc2ccc(cc2)C#N)CC1)c1ccc(cn1)C(=O)Nc1cccc(Cc2ccccc2)c1 Show InChI InChI=1S/C33H31N5O2/c34-21-25-9-11-26(12-10-25)23-38-17-15-29(16-18-38)36-33(40)31-14-13-28(22-35-31)32(39)37-30-8-4-7-27(20-30)19-24-5-2-1-3-6-24/h1-14,20,22,29H,15-19,23H2,(H,36,40)(H,37,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327866 (N2-(1-(4- cyanobenzyl)piperidin-4- yl)-N5-(3- benz...) Show SMILES O=C(NC1CCN(Cc2ccc(cc2)C#N)CC1)c1ccc(cn1)C(=O)Nc1cccc(Cc2ccccc2)c1 Show InChI InChI=1S/C33H31N5O2/c34-21-25-9-11-26(12-10-25)23-38-17-15-29(16-18-38)36-33(40)31-14-13-28(22-35-31)32(39)37-30-8-4-7-27(20-30)19-24-5-2-1-3-6-24/h1-14,20,22,29H,15-19,23H2,(H,36,40)(H,37,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair