Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328260'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328260 (N-(4-(4-cyanophenoxy) cyclohexyl)-6-(4-(4- (methy...) Show SMILES CS(=O)(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)NC2CCC(CC2)Oc2ccc(cc2)C#N)cc1 |(-14.82,.62,;-14.05,1.95,;-15.39,2.72,;-13.28,3.29,;-12.72,1.18,;-11.34,1.93,;-10,1.15,;-10,-.38,;-8.67,-1.15,;-7.34,-.38,;-6,-1.15,;-4.67,-.38,;-4.67,1.15,;-6,1.93,;-7.34,1.15,;-3.33,1.93,;-3.33,3.47,;-2,1.15,;-2,-.38,;-.67,-1.15,;.67,-.38,;.67,1.15,;-.67,1.93,;2,-1.15,;2,-2.69,;3.33,-.38,;4.67,-1.15,;4.67,-2.69,;6,-3.47,;7.34,-2.69,;7.34,-1.15,;6,-.38,;8.67,-3.47,;10,-2.69,;11.34,-3.47,;12.67,-2.69,;12.72,-1.13,;11.34,-.39,;10,-1.15,;14.05,-.36,;15.38,.41,;-11.34,-1.15,;-12.67,-.38,)| Show InChI InChI=1S/C32H34N4O6S/c1-43(39,40)29-13-11-27(12-14-29)42-28-16-18-36(19-17-28)32(38)30-15-4-23(21-34-30)31(37)35-24-5-9-26(10-6-24)41-25-7-2-22(20-33)3-8-25/h2-4,7-8,11-15,21,24,26,28H,5-6,9-10,16-19H2,1H3,(H,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair