Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328263'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328263 (N-(1-(4- acetamidobenzyl) piperidin-4-yl)-6-(4-(4...) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cn1)C(=O)NC1CCN(Cc2ccc(NC(C)=O)cc2)CC1 Show InChI InChI=1S/C34H39N5O5/c1-23(40)36-28-8-3-24(4-9-28)22-38-17-15-29(16-18-38)37-33(42)27-7-12-31(35-21-27)34(43)39-19-13-26(14-20-39)32(41)25-5-10-30(44-2)11-6-25/h3-12,21,26,29H,13-20,22H2,1-2H3,(H,36,40)(H,37,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328263 (N-(1-(4- acetamidobenzyl) piperidin-4-yl)-6-(4-(4...) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cn1)C(=O)NC1CCN(Cc2ccc(NC(C)=O)cc2)CC1 Show InChI InChI=1S/C34H39N5O5/c1-23(40)36-28-8-3-24(4-9-28)22-38-17-15-29(16-18-38)37-33(42)27-7-12-31(35-21-27)34(43)39-19-13-26(14-20-39)32(41)25-5-10-30(44-2)11-6-25/h3-12,21,26,29H,13-20,22H2,1-2H3,(H,36,40)(H,37,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair