Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328264'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328264 (6-(4-(4-acetylphenoxy) piperidine-1-carbonyl)- N-...) Show SMILES CC(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)Nc2ccc(Oc3ccc(cc3)C#N)nc2)cc1 Show InChI InChI=1S/C32H27N5O5/c1-21(38)23-4-10-26(11-5-23)41-28-14-16-37(17-15-28)32(40)29-12-6-24(19-34-29)31(39)36-25-7-13-30(35-20-25)42-27-8-2-22(18-33)3-9-27/h2-13,19-20,28H,14-17H2,1H3,(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
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