Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328276'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328276 (6-(4-(3- acetamidophenoxy) piperidine-1-carbonyl)...) Show SMILES CC(=O)Nc1cccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)Nc2ccc(Oc3ccc(F)cc3)nc2)c1 Show InChI InChI=1S/C31H28FN5O5/c1-20(38)35-23-3-2-4-27(17-23)41-26-13-15-37(16-14-26)31(40)28-11-5-21(18-33-28)30(39)36-24-8-12-29(34-19-24)42-25-9-6-22(32)7-10-25/h2-12,17-19,26H,13-16H2,1H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328276 (6-(4-(3- acetamidophenoxy) piperidine-1-carbonyl)...) Show SMILES CC(=O)Nc1cccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)Nc2ccc(Oc3ccc(F)cc3)nc2)c1 Show InChI InChI=1S/C31H28FN5O5/c1-20(38)35-23-3-2-4-27(17-23)41-26-13-15-37(16-14-26)31(40)28-11-5-21(18-33-28)30(39)36-24-8-12-29(34-19-24)42-25-9-6-22(32)7-10-25/h2-12,17-19,26H,13-16H2,1H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair