Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328283'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328283 (6-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-N-(1...) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCC(CC1)NC(=O)c1ccc(nc1)C(=O)N1CCC(CC1)Oc1ccc(F)cc1 Show InChI InChI=1S/C30H33FN4O5S/c1-41(38,39)27-9-5-24(6-10-27)34-16-12-23(13-17-34)33-29(36)21-2-11-28(32-20-21)30(37)35-18-14-26(15-19-35)40-25-7-3-22(31)4-8-25/h2-11,20,23,26H,12-19H2,1H3,(H,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
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