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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328288'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5'-AMP-activated protein kinase catalytic subunit alpha-2


(Homo sapiens (Human))		BDBM328288
PNG
(N-((3S,4R)-3-fluoro-1- ((5-methylisoxazol-3- yl)me...)
Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cn1)C(=O)NC1CCN(Cc2cc(C)on2)C[C@@H]1F |r|
Show InChI InChI=1S/C30H34FN5O5/c1-19-15-23(34-41-19)17-35-12-11-26(25(31)18-35)33-29(38)22-5-8-27(32-16-22)30(39)36-13-9-21(10-14-36)28(37)20-3-6-24(40-2)7-4-20/h3-8,15-16,21,25-26H,9-14,17-18H2,1-2H3,(H,33,38)/t25-,26?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<500n/an/an/an/a



Rigel Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...

US Patent US9663496 (2017)


BindingDB Entry DOI: 10.7270/Q26975P8
More data for this
Ligand-Target Pair