Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328296'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328296 (N-((cis)-4-(4- cyanophenoxy) cyclohexyl)-6-(4-(3-...) Show SMILES O=C(Nc1cccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)NC2CC[C@@H](CC2)Oc2ccc(cc2)C#N)c1)C1CC1 |r,wU:29.34,(-13.9,1.15,;-13.9,-.38,;-12.57,-1.15,;-11.23,-.38,;-11.23,1.15,;-9.9,1.93,;-8.57,1.15,;-8.57,-.38,;-7.23,-1.15,;-5.9,-.38,;-4.56,-1.15,;-3.23,-.38,;-3.23,1.15,;-4.56,1.93,;-5.9,1.15,;-1.9,1.93,;-1.9,3.47,;-.56,1.15,;-.56,-.38,;.77,-1.15,;2.1,-.38,;2.1,1.15,;.77,1.93,;3.44,-1.15,;3.44,-2.69,;4.77,-.38,;6.1,-1.15,;6.1,-2.69,;7.44,-3.47,;8.77,-2.69,;8.77,-1.15,;7.44,-.38,;10.11,-3.47,;11.44,-2.69,;12.77,-3.47,;14.11,-2.69,;14.15,-1.13,;12.77,-.38,;11.44,-1.15,;15.49,-.36,;16.82,.41,;-9.9,-1.15,;-15.23,-1.15,;-16.77,-1.15,;-16,-2.49,)| Show InChI InChI=1S/C35H37N5O5/c36-21-23-4-11-28(12-5-23)44-29-13-9-26(10-14-29)38-34(42)25-8-15-32(37-22-25)35(43)40-18-16-30(17-19-40)45-31-3-1-2-27(20-31)39-33(41)24-6-7-24/h1-5,8,11-12,15,20,22,24,26,29-30H,6-7,9-10,13-14,16-19H2,(H,38,42)(H,39,41)/t26?,29-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair