Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328301'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328301 (N-(1-(4-methoxybenzyl) piperidin-4-yl)-6-(4-(4- (...) Show SMILES COc1ccc(CN2CCC(CC2)NC(=O)c2ccc(nc2)C(=O)N2CCC(CC2)C(=O)c2ccc(cc2)N2CCCC2)cc1 Show InChI InChI=1S/C36H43N5O4/c1-45-32-11-4-26(5-12-32)25-39-20-16-30(17-21-39)38-35(43)29-8-13-33(37-24-29)36(44)41-22-14-28(15-23-41)34(42)27-6-9-31(10-7-27)40-18-2-3-19-40/h4-13,24,28,30H,2-3,14-23,25H2,1H3,(H,38,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328301 (N-(1-(4-methoxybenzyl) piperidin-4-yl)-6-(4-(4- (...) Show SMILES COc1ccc(CN2CCC(CC2)NC(=O)c2ccc(nc2)C(=O)N2CCC(CC2)C(=O)c2ccc(cc2)N2CCCC2)cc1 Show InChI InChI=1S/C36H43N5O4/c1-45-32-11-4-26(5-12-32)25-39-20-16-30(17-21-39)38-35(43)29-8-13-33(37-24-29)36(44)41-22-14-28(15-23-41)34(42)27-6-9-31(10-7-27)40-18-2-3-19-40/h4-13,24,28,30H,2-3,14-23,25H2,1H3,(H,38,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair