Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2' and Ligand = 'BDBM328306'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328306 (6-(4-(4-(pyrrolidin-1- yl)benzoyl)piperidine-1- ca...) Show SMILES O=C(NC1CCN(Cc2ccc(cc2)N2CCCC2)CC1)c1ccc(nc1)C(=O)N1CCC(CC1)C(=O)c1ccc(cc1)N1CCCC1 Show InChI InChI=1S/C39H48N6O3/c46-37(30-7-12-35(13-8-30)44-21-3-4-22-44)31-15-25-45(26-16-31)39(48)36-14-9-32(27-40-36)38(47)41-33-17-23-42(24-18-33)28-29-5-10-34(11-6-29)43-19-1-2-20-43/h5-14,27,31,33H,1-4,15-26,28H2,(H,41,47)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328306 (6-(4-(4-(pyrrolidin-1- yl)benzoyl)piperidine-1- ca...) Show SMILES O=C(NC1CCN(Cc2ccc(cc2)N2CCCC2)CC1)c1ccc(nc1)C(=O)N1CCC(CC1)C(=O)c1ccc(cc1)N1CCCC1 Show InChI InChI=1S/C39H48N6O3/c46-37(30-7-12-35(13-8-30)44-21-3-4-22-44)31-15-25-45(26-16-31)39(48)36-14-9-32(27-40-36)38(47)41-33-17-23-42(24-18-33)28-29-5-10-34(11-6-29)43-19-1-2-20-43/h5-14,27,31,33H,1-4,15-26,28H2,(H,41,47)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair