Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5'-nucleotidase (Homo sapiens (Human)) | BDBM26994 (CHEMBL68253 | H2NSO3H | sulfamic acid) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.21E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM26994 (CHEMBL68253 | H2NSO3H | sulfamic acid) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.21E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM26994 (CHEMBL68253 | H2NSO3H | sulfamic acid) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
COMSATS Institute of Information Technology Curated by ChEMBL | Assay Description Inhibition of human recombinant ecto-5'-nucleotidase expressed in african green monkey COS7 cells using adenosine monophosphate as substrate preincub... | Eur J Med Chem 70: 685-91 (2013) Article DOI: 10.1016/j.ejmech.2013.10.053 BindingDB Entry DOI: 10.7270/Q279464P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM26994 (CHEMBL68253 | H2NSO3H | sulfamic acid) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.73E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM26994 (CHEMBL68253 | H2NSO3H | sulfamic acid) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
COMSATS Institute of Information Technology Curated by ChEMBL | Assay Description Inhibition of rat recombinant ecto-5'-nucleotidase expressed in african green monkey COS7 cells using adenosine monophosphate as substrate preincubat... | Eur J Med Chem 70: 685-91 (2013) Article DOI: 10.1016/j.ejmech.2013.10.053 BindingDB Entry DOI: 10.7270/Q279464P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM26994 (CHEMBL68253 | H2NSO3H | sulfamic acid) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.73E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair |