BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50016013'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.				J Med Chem 39: 3491-502 (1996) Article DOI: 10.1021/jm960188q BindingDB Entry DOI: 10.7270/Q2XW4HXS
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 1319-28 (2010) Article DOI: 10.1021/jm9015763 BindingDB Entry DOI: 10.7270/Q2T154KK
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to inhibit 5-HT sensitive,forskolin-stimulated adenylyl cyclase(FSC) activity in rat hippocampal membranes mediated through 5-hydroxytryptami...				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair