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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50265777'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50265777
PNG
(CHEMBL461023 | N-[4-(3,4-Dihydro-6-methoxypyrazino...)
Show SMILES COc1cccc2cc3CN(CCCCNC(=O)C4=NCc5ccccc5C4)CCn3c12 |t:18|
Show InChI InChI=1S/C26H30N4O2/c1-32-24-10-6-9-20-15-22-18-29(13-14-30(22)25(20)24)12-5-4-11-27-26(31)23-16-19-7-2-3-8-21(19)17-28-23/h2-3,6-10,15H,4-5,11-14,16-18H2,1H3,(H,27,31)
PDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 28n/an/an/an/an/an/an/an/a



University of Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A receptor in CRL:CD(SD)BR-COBS rat hippocampus by scintillation spectrometry

J Med Chem 52: 151-69 (2009)


Article DOI: 10.1021/jm800689g
BindingDB Entry DOI: 10.7270/Q2J67GSD
More data for this
Ligand-Target Pair