BindingDB PrimarySearch

Found 9 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1B' and Ligand = 'BDBM81498'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by PDSP K_i Database									J Pharmacol Exp Ther 260: 614-26 (1992) BindingDB Entry DOI: 10.7270/Q2SJ1J3M
University of Texas Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.				J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Mus musculus (Mouse))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by PDSP K_i Database									Biochem Biophys Res Commun 184: 752-9 (1992) Article DOI: 10.1016/0006-291x(92)90654-4 BindingDB Entry DOI: 10.7270/Q2ST7NB1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 \|t:9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair