Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50265376 (CHEMBL496739 | N-(4-(4-(m-Tolyl)piperazin-1-yl)but...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Binding affinity to 5HT2A receptor (unknown origin) | J Med Chem 57: 9578-97 (2014) Article DOI: 10.1021/jm501119j BindingDB Entry DOI: 10.7270/Q2571DM0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50265376 (CHEMBL496739 | N-(4-(4-(m-Tolyl)piperazin-1-yl)but...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 15.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Siena Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometry | J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50265376 (CHEMBL496739 | N-(4-(4-(m-Tolyl)piperazin-1-yl)but...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 15.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometry | J Med Chem 52: 151-69 (2009) Article DOI: 10.1021/jm800689g BindingDB Entry DOI: 10.7270/Q2J67GSD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50265376 (CHEMBL496739 | N-(4-(4-(m-Tolyl)piperazin-1-yl)but...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Intrinsic activity at 5HT2A receptor in Wistar rat aorta | J Med Chem 52: 151-69 (2009) Article DOI: 10.1021/jm800689g BindingDB Entry DOI: 10.7270/Q2J67GSD | |||||||||||
More data for this Ligand-Target Pair |