Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM30707![]() (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Research, Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cells | J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (BOVINE) | BDBM30707![]() (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Stanford University Curated by PDSP Ki Database | J Neurosci 9: 3482-90 (1989) BindingDB Entry DOI: 10.7270/Q2FX77Z2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (RAT) | BDBM30707![]() (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 83.2 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description The binding affinity to 5-hydroxytryptamine 2B receptor of rat fundus | J Med Chem 25: 68-70 (1982) BindingDB Entry DOI: 10.7270/Q2902507 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (RAT) | BDBM30707![]() (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd. Curated by ChEMBL | Assay Description Activity against 5HT2B receptor in longitudinal stomach fundus strips in wistar rats | J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW | |||||||||||
More data for this Ligand-Target Pair |