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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B' and Ligand = 'BDBM50477831'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50477831
PNG
(CHEMBL253591)
Show SMILES C[C@H]1CNCCc2cc(Cl)c(Cl)cc12
Show InChI InChI=1S/C11H13Cl2N/c1-7-6-14-3-2-8-4-10(12)11(13)5-9(7)8/h4-5,7,14H,2-3,6H2,1H3/t7-/m0/s1
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n/an/an/an/a 40n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as intracellular IP3 accumulation

J Med Chem 51: 305-13 (2008)


Article DOI: 10.1021/jm0709034
BindingDB Entry DOI: 10.7270/Q26Q211B
More data for this
Ligand-Target Pair